This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
14.3.3 gamma antibody
catalog :
MBS533014
quantity :
0.1 ml
price :
360 USD
clonality :
monoclonal
host :
mouse
reactivity :
human, mouse
application :
western blot, ELISA, enzyme immunoassay
product information
catalog number :
MBS533014
products type :
Antibody
products full name :
14.3.3 gamma antibody
products short name :
14.3.3 gamma
products name syn :
Monoclonal 14.3.3 gamma; Anti-14.3.3 gamma; 14.3.3 gamma; 14-3-3 gamma; Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; Tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein gamma polypeptide.; KCIP 1; 14/3/3 gamma; Protein kinase C inhibitor protein 1; YWHAG; KCIP1; 3 monooxygenase/tryptophan 5 monooxgenase activation protein gamma polypeptide; 14 3 3 protein gamma subtype; gamma polypeptide 14 3 3 protein gamma; gamma polypeptide; 14 3 3gamma
other names :
14-3-3 protein gamma; 14-3-3 protein gamma; 14-3-3 protein gamma; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma; Protein kinase C inhibitor protein 1; KCIP-1
products gene name :
14.3.3 gamma
other gene names :
YWHAG; YWHAG; PPP1R170; 14-3-3GAMMA; KCIP-1
uniprot entry name :
1433G_HUMAN
clonality :
Monoclonal
isotype :
IgG2b kappa
clone :
J3H10
host :
Mouse
reactivity :
Human, Mouse
sequence length :
247
specificity :
Human
purity :
14-3-3 gamma antibody was purified by protein-G affinity chromatography
form :
Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
concentration :
1 mg/ml
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
WB: 1:1,000-1:2,000
other info1 :
Source Note: Anti-human 14-3-3 gamma antibody, clone J3H10, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human 14-3-3 gamma protein. Biological Significance: The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms,beta, gamma,epsilon, sigma, zeta, tau and theta that have been identified in mammals. The 14-3-3 gamma, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
other info2 :
Immunogen: 14-3-3 gamma antibody was raised in mouse using recombinant human 14-3-3 gamma (1-247aa) purified from E Coli as the immunogen.
products categories :
Signal Transduction
products description :
Mouse monoclonal 14-3-3 gamma antibody
ncbi gi num :
21464101
ncbi acc num :
NP_036611.2
ncbi gb acc num :
NM_012479.3
uniprot acc num :
P61981
ncbi mol weight :
28,303 Da
ncbi pathways :
Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Anchoring Of The Basal Body To The Plasma Membrane Pathway 1127503!!Apoptosis Pathway 105648!!Assembly Of The Primary Cilium Pathway 1127502!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Cell Cycle Pathway 530733!!Cell Cycle Checkpoints Pathway 105739!!Cell Cycle, Mitotic Pathway 105765!!Cell Cycle Pathway 198811
ncbi summary :
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]
size :
0.1 ml
price :
360 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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