catalog number :
MBS532881
products full name :
Synaptopodin antibody
products short name :
Synaptopodin
products name syn :
Monoclonal Synaptopodin; Anti Synaptopodin; Synaptopodin; Podocyte protein
other names :
synaptopodin; Synaptopodin
other gene names :
SYNPO; KIAA1029
uniprot entry name :
SYNPO_HUMAN
reactivity :
Bovine, Rat, Mouse, Guinea Pig, Gerbil
specificity :
Rat kidney glomeruli
purity :
Synaptopodin antibody was purified by Protein A affinity chromatography
form :
Supplied in lyophilized form. Reconstitute in 1 ml distilled water, final solution contains 0.09% sodium azide, 0.5% BSA in PBS buffer, pH 7.4
concentration :
50 ug lyophilized
storage stability :
Store at 2-8 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB)
app notes :
IHC: 1:5 - 1:10
other info1 :
Biological Significance: Synaptopodin is a protein that in humans is encoded by the SYNPO gene. Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes.
other info2 :
Immunogen: Synaptopodin antibody was raised in mouse using Isolated rat kidney glomeruli as the immunogen.
products categories :
Cancer
products description :
Mouse monoclonal Synaptopodin antibody
ncbi acc num :
AAQ07403.1
ncbi mol weight :
73,667 Da
uniprot summary :
SYNPO: an actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity. Protein type: Cytoskeletal; Actin-binding. Chromosomal Location of Human Ortholog: 5q33.1. Cellular Component: postsynaptic membrane; tight junction; cytoplasm; postsynaptic density; stress fiber; dendritic spine; perikaryon; actin cytoskeleton. Molecular Function: protein binding; actin binding. Biological Process: regulation of stress fiber formation; positive regulation of actin filament bundle formation