catalog number :
MBS532724
products full name :
ApoA-I antibody
products short name :
ApoA-I
products name syn :
Monoclonal ApoA-I; Anti-ApoA-I; Apolipoprotein A-I; ApoA I; Apo AI; ApoA1
other names :
apolipoprotein A-I preproprotein; Apolipoprotein A-I; apolipoprotein A-I; apolipoprotein A-I; Apolipoprotein A1
products gene name :
ApoA-I
other gene names :
APOA1; APOA1; Apo-AI; ApoA-I; ProapoA-I
uniprot entry name :
APOA1_HUMAN
form :
Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
concentration :
1.0 mg/ml
storage stability :
Store at 4 degree C for short term storage. Store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA: 1:10,000. WB: 1:500-1:2000
other info1 :
Biological Significance: Apolipoprotein A-I is a protein that in humans is encoded by the APOA1 gene. It has a specific role in lipid metabolism. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in plasma. Chylomicrons secreted from the intestinal enterocyte also contain ApoA1 but it is quickly transferred to HDL in the bloodstream.
other info2 :
Immunogen: ApoA-I antibody was raised in Mouse using a purified recombinant fragment of human APOA1 expressed in E Coli as the immunogen.
products categories :
Nutrition & Metabolism
products description :
Mouse monoclonal ApoA-I antibody
ncbi acc num :
NP_000030.1
ncbi gb acc num :
NM_000039.1
ncbi mol weight :
30,778 Da
ncbi pathways :
ABC-family Proteins Mediated Transport Pathway 106573!!ABCA Transporters In Lipid Homeostasis Pathway 477112!!African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Amyloids Pathway 366238!!Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Chylomicron-mediated Lipid Transport Pathway 106157!!Disease Pathway 530764!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911!!Fat Digestion And Absorption Pathway 194385
ncbi summary :
This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. [provided by RefSeq, Jul 2008]