product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD8 antibody (FITC)
catalog :
MBS532695
quantity :
100 Tests
price :
275 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
UCH-T4
reactivity :
human
application :
immunohistochemistry, flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS532695
products type :
Antibody
products full name :
CD8 antibody (FITC)
products short name :
CD8
products name syn :
Monoclonal CD8; Anti-CD8; CD 8; CD8; CD-8
other names :
CD8 antigen, partial; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein CD8 beta chain; CD8b molecule; CD_antigen: CD8b
products gene name :
CD8
other gene names :
CD8B; CD8B; LY3; P37; LEU2; LYT3; CD8B1; CD8B1
uniprot entry name :
CD8B_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
UCH-T4
host :
Mouse
reactivity :
To be determined by end-user
sequence length :
192
specificity :
Human
form :
Supplied as a liquid in PBS, with NaN3 added as preservative.
concentration :
0.2 mg/ml
storage stability :
Store at 4 degree C.
tested application :
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC)
other info1 :
Biological Significance: CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Tag/Conjugate: FITC. Immunogen: CD8 antibody (FITC) was raised in mouse using human CD8 as the immunogen.
products categories :
Immunology; Conjugated Monoclonal Antibodies
products description :
Mouse monoclonal CD8 antibody (FITC)
ncbi gi num :
178673
ncbi acc num :
AAA52283.1
uniprot acc num :
P10966
ncbi mol weight :
22,237 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Antigen Processing And Presentation Pathway 83074!!Antigen Processing And Presentation Pathway 485!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Disease Pathway 530764!!Downstream Signaling In Naive CD8+ T Cells Pathway 138018!!HIV Infection Pathway 105983!!Hematopoietic Cell Lineage Pathway 83078!!Hematopoietic Cell Lineage Pathway 489
ncbi summary :
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
size :
100 Tests
price :
275 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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