catalog number :
MBS532510
products full name :
TFPI antibody
products short name :
TFPI
products name syn :
Monoclonal TFPI; Anti-TFPI; Anti TFPI; TFPI; Tissue Factor Pathway Inhibitor
other names :
tissue factor pathway inhibitor; Tissue factor pathway inhibitor; tissue factor pathway inhibitor; Extrinsic pathway inhibitor; EPI; Lipoprotein-associated coagulation inhibitor; LACI
products gene name :
TFPI
other gene names :
TFPI; TFPI; EPI; LACI; TFPI1; TFPI; EPI; LACI
uniprot entry name :
TFPI1_MACMU
reactivity :
Neutralizes TFPI inhibition of TF/Vlla assay with chromogen substrate for Vlla, and TFPI inhibition (partly) in a diluted Prothrombine test.
form :
Liquid in 20mM TRIS, 150mM Sodium Azide, pH8.0. No preservatives added.
concentration :
2.0 mg/ml
storage stability :
4 degree C shipping only. Upon receipt store at -20 degree C. Avoid repeated freeze/thaw cycles. Suitable for use in ELISA as tracer antibody for Human TFPI.
tested application :
ELISA (EIA), Flow Cytometry (FC/FACS), Western Blot (WB)
app notes :
Optimal conditions to be determined by end user.
other info1 :
Biological Significance: Tissue factor pathway inhibitor (or TFPI) is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) and Thrombin (Factor IIa). While Xa is inhibited, the Xa-TFPI complex can subsequently also inhibit the FVIIa-tissue factor complex. TFPI contributes significantly to the inhibition of Xa in vivo, despite being present at concentrations of only 2.5 nM.
other info2 :
Immunogen: Kunitz domain 1 (aa12-88)
products categories :
Nutrition & Metabolism
products description :
Mouse monoclonal TFPI antibody
ncbi acc num :
NP_001181951.1
ncbi gb acc num :
NM_001195022.1
ncbi pathways :
Complement And Coagulation Cascades Pathway (86743); Complement And Coagulation Cascades Pathway (484)