product summary
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company name :
MyBioSource
product type :
antibody
product name :
Bradykinin Receptor antibody
catalog :
MBS532372
quantity :
0.1 mg
price :
865 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4G7
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS532372
products type :
Antibody
products full name :
Bradykinin Receptor antibody
products short name :
Bradykinin Receptor
products name syn :
Monoclonal Bradykinin Receptor; Anti-Bradykinin Receptor; B2 Bradykinin Receptor; B2 Receptor
other names :
B2 bradykinin receptor; B2 bradykinin receptor; B2 bradykinin receptor; bradykinin receptor B2
other gene names :
BDKRB2; BDKRB2; B2R; BK2; BK-2; BKR2; BRB2; BKR2; B2R; BK-2 receptor
uniprot entry name :
BKRB2_HUMAN
clonality :
Monoclonal
isotype :
IgG1 lambda
clone :
4G7
host :
Mouse
reactivity :
To be determined by end user
sequence length :
391
form :
PBS, pH 7.2.
concentration :
0.5 mg/ml
storage stability :
Aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA: 10 ug/ml. WB 1:500 - 1:2500
other info1 :
Biological Significance: The bradykinin receptor family is a group of G-protein coupled receptors whose principal ligand is the protein bradykinin. a 9 amino acid peptide generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy
other info2 :
Immunogen: Bradykinin Receptor antibody was raised in mouse using bradykinin receptor B2 partial recombinant protein with GST tag as the immunogen.
products categories :
Cardiac Markers
products description :
Mouse monoclonal Bradykinin Receptor antibody.
ncbi gi num :
4557359
ncbi acc num :
NP_000614.1
ncbi gb acc num :
NM_000623.3
uniprot acc num :
P30411
ncbi mol weight :
41,441 Da
ncbi pathways :
ACE Inhibitor Pathway (198763); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Chagas Disease (American Trypanosomiasis) Pathway (147809); Chagas Disease (American Trypanosomiasis) Pathway (147795); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Direct P53 Effectors Pathway (137939); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213307)
ncbi summary :
This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq, Jul 2008]
uniprot summary :
BKR2: a receptor for bradykinin. Bradykinin elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1. Chromosomal Location of Human Ortholog: 14q32.1-q32.2. Cellular Component: integral to plasma membrane; plasma membrane; endosome. Molecular Function: bradykinin receptor activity; protein binding; protease binding; protein heterodimerization activity; type 1 angiotensin receptor binding; phosphoinositide phospholipase C activity. Biological Process: vasoconstriction; blood circulation; metabolic process; negative regulation of peptidyl-serine phosphorylation; arachidonic acid secretion; vasodilation; response to salt stress; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; smooth muscle contraction; cell surface receptor linked signal transduction; regulation of vasoconstriction; regulation of vascular permeability; inflammatory response; transmembrane receptor protein tyrosine kinase signaling pathway
size1 :
0.1 mg
price1 :
865 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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