product summary
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company name :
MyBioSource
product type :
antibody
product name :
Ricin antibody
catalog :
MBS532353
quantity :
1 mg
price :
645 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[CP37]
reactivity :
castor bean
application :
western blot, ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS532353
products type :
Antibody
products full name :
Ricin antibody
products short name :
[Ricin]
products name syn :
[Monoclonal Ricin; Anti-Ricin; RCA60; Ricinus Communis]
other names :
[Ricin; Ricin; Ricin precursor; Ricin A chain (EC:3.2.2.22)Alternative name(s):rRNA N-glycosidase]
other gene names :
[RCOM_2159910]
uniprot entry name :
RICI_RICCO
clonality :
Monoclonal
isotype :
IgG2a
clone :
[CP37]
host :
Mouse
reactivity :
This anitbody recognizes the A-chain of RCA60
sequence length :
576
purity :
Ricin antibody was purified by chromatography on protein G Sepharose.
form :
Liquid in PBS (pH7.4) with 0.09% Sodium Azide as presevative.
concentration :
3.5mg/ml
storage stability :
Store at 4°C. Do Not Freeze!
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Biological Significance: Ricin is a toxalbumin which may be extracted from the castor bean. Ricin is poisonous if inhaled, injected, or ingested, acting as a toxin by the inhibition of protein synthesis. It is resistant, but not impervious, to digestion by peptidases.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
products categories :
Drugs & Toxicology
products description :
Mouse monoclonal Ricin antibody
ncbi gi num :
132567
ncbi acc num :
P02879.1
uniprot acc num :
P02879
uniprot summary :
Ricin is highly toxic to animal cells and to a lesser extent to plant cells. The A chain acts as a glycosidase that removes a specific adenine residue from an exposed loop of the 28S rRNA (A4324 in mammals), leading to rRNA breakage. As this loop is involved in elongation factor binding, modified ribosomes are catalytically inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, faster than the cell can make new ones. Therefore a single A chain molecule can kill an animal cell. The B chain binds to beta-D-galactopyranoside moieties on cell surface glycoproteins and glycolipids and facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (Lectin activity).
size1 :
1 mg
price1 :
645 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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