catalog number :
MBS532342
products full name :
CD9 antibody
products short name :
CD9
products name syn :
Monoclonal CD9; Anti-CD9; CD-9; CD 9; CD9
other names :
CD9 antigen; CD9 antigen; CD9 antigen; CD9 molecule; 5H9 antigen; Cell growth-inhibiting gene 2 protein; Leukocyte antigen MIC3; Motility-related protein; MRP-1; Tetraspanin-29; Tspan-29; p24; CD_antigen: CD9
other gene names :
CD9; CD9; MIC3; MRP-1; BTCC-1; DRAP-27; TSPAN29; TSPAN-29; MIC3; TSPAN29; MRP-1; Tspan-29
uniprot entry name :
CD9_HUMAN
form :
Supplied as a liquid in 100mM BBS, pH 8.2.
concentration :
0.1 mg/ml
storage stability :
Store at 4 degree C.
tested application :
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
other info1 :
Biological Significance: CD9 antigen is a protein that in humans is encoded by the CD9 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
other info2 :
Immunogen: CD9 antibody was raised in mouse using human CD9 as the immunogen.
products categories :
Immunology
products description :
Mouse monoclonal CD9 antibody
ncbi acc num :
NP_001760.1
ncbi gb acc num :
NM_001769.3
ncbi mol weight :
25,416 Da
ncbi pathways :
Disease Pathway (530764); Fertilization Pathway (833797); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Hemostasis Pathway (106028); Infectious Disease Pathway (1183535); Platelet Activation, Signaling And Aggregation Pathway (106034); Platelet Degranulation Pathway (106050); Reproduction Pathway (833796); Response To Elevated Platelet Cytosolic Ca2+ Pathway (106048)
ncbi summary :
This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]
uniprot summary :
CD9: Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion. Belongs to the tetraspanin (TM4SF) family. Protein type: Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 12p13.3. Cellular Component: extracellular space; platelet alpha granule membrane; focal adhesion; integral to plasma membrane; apical plasma membrane; plasma membrane; vesicle; external side of plasma membrane. Molecular Function: integrin binding; protein binding. Biological Process: platelet activation; fusion of sperm to egg plasma membrane; pathogenesis; multicellular organism reproduction; paranodal junction assembly; negative regulation of cell proliferation; platelet degranulation; single fertilization; brain development; blood coagulation; oligodendrocyte development; cell motility; cell adhesion; response to water deprivation