catalog number :
MBS532330
products full name :
CD28 antibody
products short name :
CD28
products name syn :
Monoclonal CD28; Anti-CD28; CD28; CD 28; CD-28
other names :
CD28, partial; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28; CD28 antigen; CD_antigen: CD28
products gene name :
CD28
other gene names :
Cd28; Cd28
uniprot entry name :
CD28_MOUSE
reactivity :
To be determined by end-user
form :
Supplied as a liquid in 100mM BBS, pH 8.2.
concentration :
0.5 mg/ml
storage stability :
Store at 4 degree C.
tested application :
Flow Cytometry (FC/FACS), Immunoprecipitation (IP)
other info1 :
Biological Significance: CD28 (Cluster of Differentiation 28) is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for B7.1 (CD80) and B7.2 (CD86). When activated by Toll-like receptor ligands, the B7.1 expression is upregulated in antigen presenting cells (APCs). The B7.2 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
other info2 :
Immunogen: CD28 antibody was raised in hamster using CD28 costimulatory receptor as the immunogen.
products categories :
Immunology
products description :
Hamster monoclonal CD28 antibody
ncbi acc num :
AAA37396.1
ncbi mol weight :
25,243 Da
ncbi pathways :
Adaptive Immune System Pathway 1168853!!Allograft Rejection Pathway 83316!!Allograft Rejection Pathway 535!!Autoimmune Thyroid Disease Pathway 83314!!Autoimmune Thyroid Disease Pathway 533!!CD28 Co-stimulation Pathway 1168860!!CD28 Dependent PI3K/Akt Signaling Pathway 1168861!!CD28 Dependent Vav1 Pathway 1168862!!Cell Adhesion Molecules (CAMs) Pathway 83266!!Cell Adhesion Molecules (CAMs) Pathway 480