catalog number :
MBS532219
products full name :
CD62P antibody
products short name :
CD62P
products name syn :
Monoclonal CD62P; Anti-CD62P; CD 62P; CD-62P; CD62P; P-Selectin
other names :
CD62P, partial; CD62P; CD62P
products gene name :
CD62P
uniprot entry name :
F2VQT1_EPICO
reactivity :
Murine CD62P
form :
Supplied lyophilized from PBS, with 5% Trehalose. Reconstitute with sterile PBS.
concentration :
500 ug per vial: lyophilized
storage stability :
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA: 2-8 ug/mL. WB: 1 ug/mL
other info1 :
Biological Significance: Mouse P-Selectin (GMP140, LECAM3, PADGEM, CD62P), a member of the Selectin family, is a cell surface glycoprotein expressed by activated platelets and endothelial cells. P-Selectin is translocated to the cell surface within minutes, from alpha granules of platelets or WeibelPalade bodies of endothelial cells, following stimulation with thrombin, histamine, PMA or peroxides. P-Selectin binds to a 106 kDa protein present on myeloid cells, neutrophils, monocytes and lymphocytes, termed PSGL 1 (PSelectin glycoprotein ligand). P-Selectin plays a role in the adhesion of leukocytes and neutrophils to the endothelium. Acting in cooperation with L-Selectin, P-Selectin mediates the initial interaction of circulating leukocytes with endothelial cells that produces a characteristic ?rolling? of the leukocytes on the endothelium.
other info2 :
Immunogen: CD62P antibody was raised in mouse using mouse myeloma cell line NS0-derived recombinant mouse PSelectin/CD62P as the immunogen.
products categories :
Immunology
products description :
Mouse monoclonal CD62P antibody
ncbi acc num :
AEA39677.1
ncbi mol weight :
4,860 Da