catalog number :
MBS532007
products full name :
Leptin antibody
products short name :
Leptin
products name syn :
Monoclonal Leptin; Anti-Leptin; Obesity; OB; Leptin; Anti Leptin
other names :
leptin; leptin; leptin
other gene names :
lep; ob; xlep
reactivity :
Human leptin
form :
Lyophilized from PBS.
concentration :
500ug lyophilized
storage stability :
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Inhibition, Western Blot (WB)
app notes :
ELISA: 2-4 ug/ml. WB: 0.2-0.4 ug/ml
other info1 :
Biological Significance: Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models.
other info2 :
Immunogen: Leptin antibody was raised in mouse using highly pure recombinant human leptin as the immunogen.
products categories :
Hormones & Steroids
products description :
Mouse monoclonal Leptin antibody
ncbi acc num :
NP_001089183.1
ncbi gb acc num :
NM_001095714.1
ncbi mol weight :
16.2 kDa (predicted detection band MW)
ncbi pathways :
Adipocytokine Signaling Pathway (119298); Adipocytokine Signaling Pathway (505); Cytokine-cytokine Receptor Interaction Pathway (119282); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (84661); Jak-STAT Signaling Pathway (488); Neuroactive Ligand-receptor Interaction Pathway (119283); Neuroactive Ligand-receptor Interaction Pathway (462)