product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Granzyme B antibody
catalog :
MBS531767
quantity :
0.2 mg
price :
745 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CLB-GB7
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS531767
products type :
Antibody
products full name :
Granzyme B antibody
products short name :
Granzyme B
products name syn :
Monoclonal Granzyme B; Anti-Granzyme B
other names :
granzyme B; Granzyme B; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); C11; CTLA-1; Cathepsin G-like 1; CTSGL1; Cytotoxic T-lymphocyte proteinase 2; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; HLP; SECT; T-cell serine protease 1-3E
other gene names :
GZMB; GZMB; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1; CGL1; CSPB; CTLA1; GRB; CTSGL1; Lymphocyte protease; HLP
uniprot entry name :
GRAB_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
CLB-GB7
host :
Mouse
reactivity :
This antibody recognizes the Granzyme B antigen, which is expressed on Human lymphocytes (CTL and NK-Cells)
sequence length :
247
form :
Liquid in 20mM TRIS, pH 8.0, with 150mM NaCl, and 0.001% Merthiolate.
storage stability :
Aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles
tested application :
User optimized
other info1 :
Biological Significance: Granzyme B is a serine protease that in humans is encoded by the GZMB gene. Granzyme B is expressed by cytotoxic T lymphocytes (CTL) and natural killer (NK) cells.
other info2 :
Immunogen: Granzyme B antibody was raised in mouse using recombinant granzyme B as the immunogen.
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Mouse monoclonal Granzyme B antibody
ncbi gi num :
221625528
ncbi acc num :
NP_004122.2
ncbi gb acc num :
NM_004131.4
uniprot acc num :
P10144
ncbi mol weight :
27,716 Da
ncbi pathways :
Activation, Myristolyation Of BID And Translocation To Mitochondria Pathway 105657!!Allograft Rejection Pathway 920963!!Allograft Rejection Pathway 83123!!Allograft Rejection Pathway 535!!Apoptosis Pathway 198797!!Apoptosis Pathway 105648!!Autoimmune Thyroid Disease Pathway 83121!!Autoimmune Thyroid Disease Pathway 533!!Caspase Cascade In Apoptosis Pathway 137974!!Downstream Signaling In Naive CD8+ T Cells Pathway 138018
ncbi summary :
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq, Jul 2008]
size :
0.2 mg
price :
745 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!