product summary
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company name :
MyBioSource
product type :
antibody
product name :
Insulin antibody
catalog :
MBS531719
quantity :
1 mg
price :
395 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M322214
reactivity :
human
application :
ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS531719
products type :
Antibody
products full name :
Insulin antibody
products short name :
Insulin
products name syn :
Monoclonal Insulin; Anti-Insulin
other names :
insulin; Insulin; insulin; insulin
other gene names :
INS; INS; IDDM; ILPR; IRDN; IDDM1; IDDM2; MODY10
uniprot entry name :
INS_HUMAN
clonality :
Monoclonal
isotype :
IgG1 kappa
clone :
M322214
host :
Mouse
reactivity :
This antibody recognizes Human proinsulin, Bovine insulin, and Pig insulin
sequence length :
110
specificity :
Human
purity :
Insulin antibody was purified by chromatography on protein A Sepharose.
form :
Protein A purified and supplied inPBS, pH 7.4, 0.1 % NaN3.
storage stability :
Store at 4 degree C.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
app notes :
MBS531719 can be used as the conjugate antibody with MBS531836 as the coating antibody.
other info1 :
Biological Significance: insulin, a hormone that regulates the level of sugar (glucose) in the blood and that is produced by the beta cells of the islets of Langerhans in the pancreas. Insulin is secreted when the level of blood glucose rises such as after a meal. When the level of blood glucose falls, secretion of insulin stops, and the liver releases glucose into the blood.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Insulin antibody was raised in mouse using human insulin as the immunogen.
products categories :
Hormones & Steroids
products description :
Mouse monoclonal Insulin antibody
ncbi gi num :
386828
ncbi acc num :
AAA59172.1
uniprot acc num :
P01308
ncbi mol weight :
21,537 Da
ncbi pathways :
AGE/RAGE Pathway 698754!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!ATF-2 Transcription Factor Network Pathway 138006!!Adipogenesis Pathway 198832!!Aldosterone-regulated Sodium Reabsorption Pathway 130626!!Aldosterone-regulated Sodium Reabsorption Pathway 130590!!Amyloids Pathway 366238!!Arf6 Trafficking Events Pathway 137954!!Cardiac Progenitor Differentiation Pathway 712094
ncbi summary :
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
size :
1 mg
price :
395 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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