product summary
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company name :
MyBioSource
product type :
antibody
product name :
Serotonin Transporter antibody
catalog :
MBS531619
quantity :
0.1 mg
price :
490 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MAB1564
reactivity :
human
application :
immunohistochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS531619
products type :
Antibody
products full name :
Serotonin Transporter antibody
products short name :
Serotonin Transporter
products name syn :
Monoclonal Serotonin Transporter; Anti-Serotonin Transporter; SERT; Anti Serotonin Transporter; Serotonin Transporter
other names :
serotonin transporter, partial; Sodium-dependent serotonin transporter; sodium-dependent serotonin transporter; solute carrier family 6 (neurotransmitter transporter), member 4; 5HT transporter; 5HTT; Solute carrier family 6 member 4
other gene names :
SLC6A4; SLC6A4; HTT; 5HTT; OCD1; SERT; 5-HTT; SERT1; hSERT; 5-HTTLPR; HTT; SERT; 5HTT
uniprot entry name :
SC6A4_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
MAB1564
host :
Mouse
reactivity :
To be determined by end-user
sequence length :
114
specificity :
Rat
purity :
Serotonin Transporter antibody was purified by Protein A affinity chromatography.
form :
0.02M PO4 buffer, pH 7.6, with 0.25M NaCl, and 0.1% NaN3.
storage stability :
Store at 4 degree C.
tested application :
Immunohistochemistry (IHC)
app notes :
IHC: 0.5-1 ug/ml
other info1 :
Biological Significance: Serotonin (5-hydroxytryptamine) is a catecholamine with a molecular weight of 176 Daltons that is formed in gastrointestinal enteroendocrine cells, platelets, brain and spinal cord. It is secreted by enterochromaffin cells (EC) in the stomach, intestines and appendix and is believed to play a role in gut motility. Serotonin is the major secretion of carcinoid tumors. It is metabolized with the production of 5-hydroxy-indoleacetic acid.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: Serotonin transporter antibody was raised in mouse using at serotonin transporter, N-terminus/GST Fusion protein (amino acids 1-85) as the immunogen.
products categories :
Neuroscience
products description :
Mouse monoclonal Serotonin Transporter antibody
ncbi gi num :
2149095
ncbi acc num :
AAB93475.1
uniprot acc num :
P31645
ncbi mol weight :
74,979 Da
ncbi pathways :
Monoamine Transport Pathway 198851!!SIDS Susceptibility Pathways 198901!!Serotonergic Synapse Pathway 525336!!Serotonin Transporter Activity Pathway 920962!!Synaptic Vesicle Pathway 672457
ncbi summary :
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
490 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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