product summary
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company name :
MyBioSource
product type :
antibody
product name :
Cingulin antibody
catalog :
MBS531532
quantity :
5 mL
price :
395 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
139.3.4
reactivity :
human, mouse, cow
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS531532
products type :
Antibody
products full name :
Cingulin antibody
products short name :
Cingulin
products name syn :
Monoclonal Cingulin; Anti-Cingulin
other names :
cingulin; Cingulin; cingulin; cingulin
other gene names :
CGN; CGN; KIAA1319
uniprot entry name :
CING_HUMAN
clonality :
Monoclonal
isotype :
IgM
clone :
139.3.4
host :
Mouse
reactivity :
Bovine, Frog, Human, Mouse
sequence length :
1203
purity :
Culture supernatant
form :
Hybridoma culture supernatant.
concentration :
5.0 ml per vial
storage stability :
Store at 4 degree C.
tested application :
Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB)
other info1 :
Biological Significance: Cingulin is a protein that in humans is encoded by the CGN gene. Cingulin is specifically localized at tight junctions in epithelial cells, unlike ZO-1, which is also detected at adherens-type junctions in non-epithelial cells. During early Xenopus embryo development, cingulin is detected at a cortical localization, and then accumulates at apical junctions, unlike ZO-1 and other junctional proteins, that are targeted to the new regions of cell-cell contact via the lateral domain.
other info2 :
Immunogen: Cingulin antibody was raised in mouse using a synthetic peptide corresponding to residues 4-24 of cingulin as the immunogen.
products categories :
Differentiation & Development
products description :
Mouse monoclonal Cingulin antibody
ncbi gi num :
16262452
ncbi acc num :
NP_065821.1
ncbi gb acc num :
NM_020770.2
uniprot acc num :
Q9P2M7
ncbi mol weight :
87,047 Da
ncbi pathways :
Signal Transduction Pathway (477114); Signaling By TGF-beta Receptor Complex Pathway (106504); TGF-beta Receptor Signaling In EMT (epithelial To Mesenchymal Transition) Pathway (645294); Tight Junction Pathway (83071); Tight Junction Pathway (482)
uniprot summary :
CGN: Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the cingulin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: tight junction; cell junction; myosin complex. Molecular Function: protein binding; microtubule binding; motor activity; actin binding. Biological Process: metabolic process; transforming growth factor beta receptor signaling pathway; microtubule cytoskeleton organization and biogenesis
size1 :
5 mL
price1 :
395 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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