This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Cytokeratin 18 antibody
catalog :
MBS531445
quantity :
0.05 mg
price :
535 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Ks18.04
reactivity :
human, mouse, rat, dog, cow, zebrafish
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
catalog number :
MBS531445
products type :
Antibody
products full name :
Cytokeratin 18 antibody
products short name :
Cytokeratin 18
products name syn :
Monoclonal Cytokeratin 18; Anti-Cytokeratin 18; Keratin K18; Cytokeratin 18; Cytokeratin -18
other names :
cytokeratin 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; keratin 18, type I; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
other gene names :
KRT18; KRT18; K18; CYK18; CYK18; CK-18; K18
uniprot entry name :
K1C18_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
Ks18.04
host :
Mouse
reactivity :
Bovine, Dog, Fish, Hamster, Human, Mouse, Pig, Rat, Sheep, Trout, Zebrafish
sequence length :
430
specificity :
Human cytokeratin 18
purity :
Protein A affinity chromatography
form :
Supplied as a lyophilized powder. Reconstitute in 1 ml dist. water (final solution contains 0.09 % NaN3, 0.5% BSA in PBS buffer, pH 7.4)
storage stability :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze-thaw cycles.
tested application :
Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB)
app notes :
IHC-P: 1:20
other info1 :
Biological Significance: Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin represents an excellent marker for the discrimination of specific subtypes of adenocarcinoma. Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Cytokeratin 18 antibody was raised in mouse using human cytokeratin 18 from HeLa cytoskeletal preparation as the immunogen.
products categories :
Cell Biology
products description :
Mouse monoclonal Cytokeratin 18 antibody
ncbi gi num :
34037
ncbi acc num :
CAA31375.1
uniprot acc num :
P05783
ncbi mol weight :
48,058 Da
ncbi pathways :
Caspase Cascade In Apoptosis Pathway 137974!!EGFR1 Signaling Pathway 198782!!Pathogenic Escherichia Coli Infection Pathway 83103!!Pathogenic Escherichia Coli Infection Pathway 672459!!Pathogenic Escherichia Coli Infection Pathway 516
ncbi summary :
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
535 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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