catalog number :
MBS531311
products full name :
CYP2C11 antibody
products short name :
CYP2C11
products name syn :
Monoclonal CYP2C11; Anti-CYP2C11; CYPC11-2; CYP2C11; Cytochrome P450 2C11; CYPC11-2; CYPC11 2; CYPC11 2
other names :
cytochrome P450 2C11; Cytochrome P450 2C11; cytochrome P450 2C11; UT-2; P450H; CYPIIC11; P450-UT-A; P-450(M-1); cytochrome P450H; cytochrome P450-UT-2; cytochrome P450-UT-A; cytochrome P-450(M-1); cytochrome P450, 2c29; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase); cytochrome P450, subfamily 2, polypeptide 11; CYPIIC11; Cytochrome P-450(M-1); Cytochrome P450-UT-2; Cytochrome P450-UT-A; Cytochrome P450H
products gene name :
CYP2C11
other gene names :
Cyp2c11; Cyp2c11; Cyp2c; CYP2CII; Cyp2c; Cyp2c-11
uniprot entry name :
CP2CB_RAT
form :
Purified Mouse IgG.
storage stability :
Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles
tested application :
ELISA (EIA), Western Blot (WB)
products categories :
Proteases, Inhibitors, Monoclonal Antibodies
products description :
Mouse monoclonal CYP2C11 antibody. The cytochrome P450 superfamily (officially abbreviated as CYP) is a large and diverse group of enzymes. The function of most CYP enzymes is to catalyze the oxidation of organic substances. The substrates of CYP enzymes include metabolic intermediates such as lipids and steroidal hormones, as well as xenobiotic substances such as drugs and other toxic chemicals.
ncbi acc num :
NP_062057.2
ncbi gb acc num :
NM_019184.2
ncbi mol weight :
57,181 Da
ncbi pathways :
Arachidonate Epoxygenase Epoxide Hydrolase Pathway 219791!!Arachidonic Acid Metabolism Pathway 83383!!Arachidonic Acid Metabolism Pathway 366!!Biological Oxidations Pathway 574084!!Cytochrome P450 - Arranged By Substrate Type Pathway 574086!!Drug Metabolism - Cytochrome P450 Pathway 83424!!Drug Metabolism - Cytochrome P450 Pathway 427!!Linoleic Acid Metabolism Pathway 83384!!Linoleic Acid Metabolism Pathway 367!!Metabolism Pathway 573935
ncbi summary :
most abundant member of the p450 xenobiotic-inducible superfamily in non-stimulated liver; metabolizes xenobiotics and testosterone [RGD, Feb 2006]
uniprot summary :
Function: Metabolizes testosterone mainly in positions 2 alpha and 16 alpha. Catalytic activity: RH + reduced flavoprotein + O2 = ROH + oxidized flavoprotein + H2O. Cofactor: Heme group . By similarity. Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Tissue specificity: Liver; male-specific. Induction: Constitutively expressed. Sequence similarities: Belongs to the cytochrome P450 family.