catalog number :
MBS531244
products full name :
Prolactin antibody
products short name :
Prolactin
products name syn :
Monoclonal Prolactin; Anti-Prolactin; hPrl; Anti Prolactin; Prolactin; hPrl
other names :
prolactin; Prolactin; prolactin; decidual prolactin; prolactin; N/A
other gene names :
PRL; PRL; PRL
uniprot entry name :
PRL_HUMAN
form :
Chromatographically purified IgG fraction supplied in 50mM PBS buffer, pH 7.5 with 0.1% NaN3.
storage stability :
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
app notes :
Matched pair antibody available for Prolactin antibody: 10-P15B
other info1 :
Immunogen: Prolactin antibody was raised in mouse using human prolactin as the immunogen.
other info2 :
Affinity Constant: 7 x 10^9 l/mol. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
products categories :
Hormones & Steroids; Monoclonal Antibodies
products description :
Mouse monoclonal Prolactin antibody. Prolactin (PRL) also known as luteotropic hormone (LTH) is a protein that in humans is encoded by the PRL gene. Prolactin is a peptide hormone primarily associated with lactation. In breastfeeding, the act of an infant suckling the nipple stimulates the production of oxytocin, which stimulates lactogenesis, in preparation for the next feed.
ncbi acc num :
NP_001157030.1
ncbi gb acc num :
NM_001163558.2
ncbi mol weight :
25,876 Da
ncbi pathways :
Amyloids Pathway 366238!!Cytokine Signaling In Immune System Pathway 366171!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Disease Pathway 530764!!ErbB4 Signaling Events Pathway 137991!!Glucocorticoid Receptor Regulatory Network Pathway 138014!!Growth Hormone Receptor Signaling Pathway 477128!!Immune System Pathway 106386!!Jak-STAT Signaling Pathway 83077
ncbi summary :
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
uniprot summary :
Function: Prolactin acts primarily on the mammary gland by promoting lactation. Subcellular location: Secreted. Sequence similarities: Belongs to the somatotropin/prolactin family. Sequence caution: The sequence CAA38264.1 differs from that shown. Reason: Frameshift at position 8.