This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
GAD65 antibody
catalog :
MBS531226
quantity :
0.1 mg
price :
665 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
9A6
application :
western blot, immunohistochemistry
product information
catalog number :
MBS531226
products type :
Antibody
products full name :
GAD65 antibody
products short name :
GAD65
products name syn :
Monoclonal GAD65; Anti-GAD65; GAD 65; Glutamic Acid Decarboxylase 65; GAD65; GAD-65
other names :
glutamic acid decarboxylase, partial; Glutamate decarboxylase 2; 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform
products gene name :
GAD65
other gene names :
GAD2; GAD65; GAD-65
uniprot entry name :
DCE2_HUMAN
clonality :
Monoclonal
isotype :
IgG1 kappa
clone :
9A6
host :
Mouse
reactivity :
Mouse, Rat
sequence length :
180
specificity :
Human
form :
PBS with 50% glycerol, pH 7.2.
concentration :
1.0 mg/ml
storage stability :
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
tested application :
Immunohistochemistry (IHC), Western Blot (WB)
app notes :
IHC: 1-10 ug/ml. WB: 1 ug/ml
other info1 :
Biological Significance: Glutamic acid decarboxylase (GAD) catalyzes formation of ?-Aminobutyric acid (GABA), which is an inhibitory neurotransmitter, and is present in brain as well as several tissues outside the central nervous system. Biological functions of GAD and GABA extend beyond regulation of neurotransmission to include effects on the immune system as well as modulation of cell proliferation, protein synthesis, and metabolism.
other info2 :
Immunogen: GAD65 antibody was raised in mouse using recombinant GST-human brain GAD65 fusion protein as the immunogen.
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Mouse monoclonal GAD65 antibody
ncbi gi num :
182942
ncbi acc num :
AAA52513.1
ncbi mol weight :
65,411 Da
uniprot summary :
GAD2: Catalyzes the production of GABA. Homodimer. Belongs to the group II decarboxylase family. Protein type: Other Amino Acids Metabolism - beta-alanine; Other Amino Acids Metabolism - taurine and hypotaurine; Lyase; EC 4.1.1.15; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - alanine, aspartate and glutamate. Chromosomal Location of Human Ortholog: 10p11.23. Cellular Component: presynaptic membrane; Golgi membrane; synaptic vesicle membrane; perinuclear region of cytoplasm; axon; plasma membrane; cytosol; cell junction. Molecular Function: protein binding; glutamate binding; glutamate decarboxylase activity; protein heterodimerization activity; pyridoxal phosphate binding. Biological Process: response to drug; synaptic transmission; glutamate decarboxylation to succinate; neurotransmitter secretion; neurotransmitter biosynthetic process
size1 :
0.1 mg
price1 :
665 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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