catalog number :
MBS531128
products full name :
CD79b antibody
products short name :
CD79b
products name syn :
Monoclonal CD79b; Anti-CD79b; CD-79b; B29; CD 79b; CD79b
other names :
B-cell antigen receptor complex-associated protein beta chain isoform 3; B-cell antigen receptor complex-associated protein beta chain; B-cell antigen receptor complex-associated protein beta chain; CD79b molecule, immunoglobulin-associated beta; B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein; CD_antigen: CD79b
products gene name :
CD79b
other gene names :
CD79B; CD79B; B29; IGB; AGM6; B29; IGB
uniprot entry name :
CD79B_HUMAN
reactivity :
To be determined by end-user
specificity :
Human CD79b
form :
100 mM BBS, pH 8.0. No preservatives added.
concentration :
0.1 mg/ml
storage stability :
Store at 4 degree C.
tested application :
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
other info1 :
Biological Significance: CD79 is a 23/21 disulfide-linked heterodimer composed of an alpha chain (CD79a/mb-1) and a Beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage and remaining through all stages of B cell differentiation prior to plasma cells. Crosslinking of the BCR leads to B cell activation. The monoclonal antibody CB3-1 reacts with the Beta chain of CD79.
other info2 :
Immunogen: CD79b antibody was raised in mouse using human CD79b as the immunogen.
products categories :
Immunology
products description :
Mouse monoclonal CD79b antibody
ncbi acc num :
NP_001035022.1
ncbi gb acc num :
NM_001039933.1
ncbi mol weight :
26,119 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway 576249!!B Cell Receptor Signaling Pathway 198909!!B Cell Receptor Signaling Pathway 83081!!B Cell Receptor Signaling Pathway 492!!BCR Signaling Pathway 138058!!Immune System Pathway 106386!!Signaling By The B Cell Receptor (BCR) Pathway 576248
ncbi summary :
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]