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antibody

ApoD antibody

MBS531063

1 ml

685 USD

monoclonal

mouse

human

immunohistochemistry, western blot, immunohistochemistry - paraffin section

MBS531063

Antibody

ApoD antibody

ApoD

Monoclonal ApoD; Anti-ApoD; Apolipoprotein D; APO D; APO-D

apolipoprotein D; Apolipoprotein D; apolipoprotein D; apo-D; apolipoprotein D; N/A

ApoD

APOD; APOD; Apo-D; ApoD

APOD_HUMAN

Monoclonal

IgG1

36C6

Mouse

Human

Lyophilized tissue culture supernatant containing 15mM NaN3. Reconstitute with 1 ml of sterile distilled water.

Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze-thaw cycles.

Immunohistochemistry (IHC) (Paraffin), Western Blot (WB)

IHC-P: 1:40-1:80, WB: 1:500-1:1,000

Immunogen: ApoD antibody was raised in mouse using prokaryotic recombinant protein corresponding to the mature full length apolipoprotein D molecule as the immunogen.

Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

Nutrition & Metabolism; Monoclonal Antibodies

Mouse monoclonal ApoD antibody. Apolipoprotein D (Apo-D) is a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It is a glycoprotein of estimated molecular weight 33 kDa. Apo-D is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism.

4502163

NP_001638.1

NM_001647.3

P05090

21,276 Da

This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008]

Function: APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. Subunit structure: Homodimer. In plasma, also exists as a disulfide-linked heterodimer with APOA2. Ref.9. Subcellular location: Secreted. Tissue specificity: Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears. Post-translational modification: N-glycosylatd. N-glycan heterogeneity at Asn-65: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor); at Asn-98: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major), dHex1Hex6HexNAc5 (minor) and dHex1Hex7HexNAc6 (minor). Miscellaneous: APOD is primarily localized in HDL (60-65%), with most of the remainder in VHDL and only trace amounts in VLDL and LDL. Sequence similarities: Belongs to the calycin superfamily. Lipocalin family.

1 ml

685 USD