product summary
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company name :
MyBioSource
product type :
antibody
product name :
Calpastatin antibody
catalog :
MBS530998
quantity :
0.1 mL
price :
745 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2G11D6
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530998
products type :
Antibody
products full name :
Calpastatin antibody
products short name :
Calpastatin
products name syn :
Monoclonal Calpastatin; Anti-Calpastatin
other names :
calpastatin, partial; Calpastatin; Calpain inhibitor; Sperm BS-17 component
other gene names :
CAST
uniprot entry name :
ICAL_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
2G11D6
host :
Mouse
reactivity :
Bovine, Dog, Human, Pig, Rabbit, Rat
sequence length :
204
specificity :
Bovine
form :
PBS-diluted ascites containing 0.05% NaN3.
concentration :
1.0 mg/ml
storage stability :
Aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin, Western Blot (WB)
app notes :
ICC: 1:1,000. WB: 1:5,000
other info1 :
Biological Significance: Calpastatin, a specific endogenous inhibitor of calpain, has a predicted molecular weight of ~77 kDa and an internal repeat of four homologous domains which allow it to inhibit multiple calpain molecules simultaneously. It functions by binding to calpain when calpain binds calcium.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Calpastatin antibody was raised in mouse using bovine skeletal muscle calpastatin as the immunogen.
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Mouse monoclonal Calpastatin antibody
ncbi gi num :
180975
ncbi acc num :
AAA52066.1
ncbi mol weight :
82,437 Da
uniprot summary :
calpastatin: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue. Belongs to the protease inhibitor I27 (calpastatin) family. 7 isoforms of the human protein are produced by alternative splicing. Protein type: Inhibitor. Chromosomal Location of Human Ortholog: 5q15. Cellular Component: membrane; cytoplasm; cytosol. Molecular Function: protein binding; endopeptidase inhibitor activity; cysteine protease inhibitor activity. Disease: Peeling Skin With Leukonychia, Acral Punctate Keratoses, Cheilitis, And Knuckle Pads
size1 :
0.1 mL
price1 :
745 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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