catalog number : 
MBS530992
products full name : 
EGF antibody
products short name : 
EGF
products name syn : 
Monoclonal EGF; Anti-EGF; egf-r; egfr; erbb1; epidermal growth factor receptor; v-erb-b homolog; panitumumab; Epidermal Growth FactorEgf receptor
other names : 
epidermal growth factor, partial; Epidermal growth factor; pro-epidermal growth factor; epidermal growth factor; Epidermal growth factor
other gene names : 
EGF; EGF; URG; HOMG4
uniprot entry name : 
Q6QBS2_HUMAN
reactivity : 
To be determined by end-user
purity : 
EGF antibody was purified by chromatography on protein G Sepharose.
form : 
Purified IgG supplied in PBS, pH 7.4, 0.1 % NaN3.
storage stability : 
Store at 4 degree C.
tested application : 
User optimized
other info1 : 
Biological Significance: Epidermal growth factor or EGF is a growth factor that plays an important role in the regulation of cell growth, proliferation, and differentiation by binding to its receptor EGFR. Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bonds.
other info2 : 
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.  Immunogen: EGF antibody was raised in mouse using human recombinant EGF as the immunogen.
products categories : 
Cytokines & Growth Factors
products description : 
Mouse monoclonal EGF antibody
ncbi acc num : 
AAS83395.1
ncbi mol weight : 
6,222 Da
ncbi pathways : 
Adaptive Immune System Pathway  366160!!Arf6 Signaling Events Pathway  138034!!Bladder Cancer Pathway  83115!!Bladder Cancer Pathway  527!!Ceramide Signaling Pathway  138023!!Choline Metabolism In Cancer Pathway  1059539!!Choline Metabolism In Cancer Pathway  1084232!!Constitutive Signaling By Aberrant PI3K In Cancer Pathway  685535!!Constitutive Signaling By EGFRvIII Pathway  1127578!!Constitutive Signaling By Ligand-Responsive EGFR Cancer Variants Pathway  530769
ncbi summary : 
This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]