product summary
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company name :
MyBioSource
product type :
antibody
product name :
14.3.3 sigma antibody
catalog :
MBS530976
quantity :
0.1 mg
price :
615 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1433S01
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530976
products type :
Antibody
products full name :
14.3.3 sigma antibody
products short name :
14.3.3 sigma
products name syn :
Monoclonal 14.3.3 Sigma; Anti-14.3.3 Sigma; 14-3-3 sigma; 14/3/3 sigma; 14.3.3 sigma; 14-3-3 Sigma
other names :
14-3-3 protein sigma; 14-3-3 protein sigma; 14-3-3 protein sigma; stratifin; Epithelial cell marker protein 1; Stratifin
products gene name :
14.3.3 sigma
other gene names :
SFN; SFN; YWHAS; HME1
uniprot entry name :
1433S_HUMAN
clonality :
Monoclonal
isotype :
IgG1 kappa
clone :
1433S01
host :
Mouse
reactivity :
To be determined by end-user
sequence length :
248
specificity :
Human
purity :
14.3.3 Sigma antibody was purified by Protein G chromatography.
form :
Antibody purified from ascites fluid by protein G chromotography and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
concentration :
0.2 mg/ml
storage stability :
Store at 4 degree C.
tested application :
Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP)
app notes :
IHC-F: 2-4 ug/ml. IHC-P: 2-4 ug/ml. IP: 2 ug/ml protein lysate
other info1 :
Biological Significance: 14-3-3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14-3-3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and apoptosis, including Raf, PKC, Bad, Cbl, and c-Bcr. Interactions between 14-3-3 and target proteins are strongly influenced by the phosphorylation state of 14-3-3 and the target protein. 14-3-3 sigma shares cyclin-Cdk2 binding motifs with different cell cycle regulators, including p107, p130, p21Cip1, p27Kip1, and p57Kip2 and is associated with cyclin-Cdk complexes in vitro and in vivo.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: 14.3.3 Sigma antibody was raised in mouse using recombinant human 14-3-3 sigma protein as the immunogen.
products categories :
Cell Biology
products description :
Mouse monoclonal 14.3.3 Sigma antibody
ncbi gi num :
5454052
ncbi acc num :
NP_006133.1
ncbi gb acc num :
NM_006142.3
uniprot acc num :
P31947
ncbi mol weight :
24,336 Da
ncbi pathways :
Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Aldosterone-regulated Sodium Reabsorption Pathway 130626!!Aldosterone-regulated Sodium Reabsorption Pathway 130590!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Apoptosis Pathway 105648!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Cell Cycle Pathway 530733!!Cell Cycle Checkpoints Pathway 105739!!Cell Cycle Pathway 83054
size :
0.1 mg
price :
615 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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