catalog number :
MBS5308580
products type :
Recombinant Protein
products full name :
Purified Recombinant CMV protein (gH pentamer complex) (His tag)
products short name :
[CMV]
products name syn :
[CMV antigen, Cytomegalovirus antigen, Cytomegalovirus protein.]
other names :
[CMV coat protein]
products gene name :
[CMV]
purity :
> 95% by SDS-PAGE
form :
0.2um filtered liquid in Dulbecco's PBS.
concentration :
1.02 mg/mL
storage stability :
Ships on dry ice. Upon receipt store at -80°C . Avoid repeat freeze/thaw cycles.
other info1 :
Grade: Recombinant. Species: Viral. Protein type: Recombinant. Additional Remarks: This recombinant, His tagged protein was expressed in 293 cells and is the gH pentamer complex. Biohazard: Recombinant protein with His tag. Use standard laboratory precautions when handling this material.
other info2 :
Tag/Conjugate: His tag. Biological Significance: The Cytomegalovirus gH Pentamer Complex is expressed on all wildtype hCMV strains but is notably missing from laboratory strains suchs as AD169. Receptor-mediated viral entry into endothelial cells requires a functional gH pentamric complex, ant his complex is one of the primary targets for antiviral antibodies in infected individuals. Implications in Disease: Most people infected with CMV who are otherwise healthy experience few if any symptoms. When first infected, some adults may have symptoms similar to mononucleosis, including fatigue, fever and muscle aches. An illness resemling infectious mononucleosis is the most common presentation of CMV in people with weakened immune systems (immunocompromised).CMV also can attack specific organs . Signs and symptoms may include: Fever, Pneumonia, Diarrhea, Ulcers in the digestive tract, Hepatitis, Inflammation of the brain ( encephalitis,) Behavorial changes ,Seizures, Coma, Visual impairment and blindness, Newbors infected with CMV in the womb (congenital CMV), babies who become infeted during birth or shortly after birth (perinatal CMV) such as through breast-feeding and people with weakened immune systems are more at risk of developing signs and symptoms than are healthy adults.
products categories :
Infectious Disease; Conjugated Proteins