MyBioSource

antibody

CKMB antibody

MBS530856

1 mg

570 USD

monoclonal

mouse

human

MBS530856

Antibody

CKMB antibody

CKMB

Monoclonal CKMB; Anti-CKMB; Creatine Kinase-MB Isoenzyme; CK-MB

creatine kinase M-type; Creatine kinase M-type; creatine kinase M-type; creatine kinase M chain; creatine kinase, muscle; Creatine kinase M chain; M-CK

CKMB

CKM; CKM; CKMM; M-CK; CKMM

KCRM_HUMAN

Monoclonal

IgG1 kappa

M9910208

Mouse

Human

Protein G purified and supplied in PBS, pH 7.3, with 0.05% NaN3.

Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Matched pair antibody available for CKMB antibody: 70-XG47

Immunogen: CKMB antibody was raised in mouse using purified human CK-MB as the immunogen.

Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Cardiac Markers; Monoclonal Antibodies

Mouse monoclonal CKMB antibody. Creatine kinase (CK) is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP). This CK enzyme reaction is reversible, such that also ATP can be generated from PCr and ADP. In the cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB.

21536288

NP_001815.2

NM_001824.4

P06732

43,101 Da

Arginine And Proline Metabolism Pathway 82957!!Arginine And Proline Metabolism Pathway 323!!Creatine Metabolism Pathway 106192!!Creatine Pathway 413359!!Creatine Pathway 468234!!Metabolism Pathway 477135!!Metabolism Of Amino Acids And Derivatives Pathway 106169!!Regulation Of Retinoblastoma Protein Pathway 137916!!Urea Cycle And Metabolism Of Amino Groups Pathway 198758!!Creatine-phosphate Biosynthesis Pathway 545319

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]

Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Catalytic activity: ATP + creatine = ADP + phosphocreatine. Subunit structure: Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Subcellular location: Cytoplasm. Sequence similarities: Belongs to the ATP:guanido phosphotransferase family.Contains 1 phosphagen kinase C-terminal domain.Contains 1 phosphagen kinase N-terminal domain.

1 mg

570 USD