product summary
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company name :
MyBioSource
product type :
protein
product name :
Purified native Human Proteinase 3 protein
catalog :
MBS5308389
quantity :
0.1 mg
price :
575 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS5308389
products type :
Native Protein
products full name :
Purified native Human Proteinase 3 protein
products short name :
[Proteinase 3]
products name syn :
[Proteinase 3, Proteinase-3, Proteinase-3 protein, PR3 protein, Proteinase 3, PR-3 protein, Proteinase 3 protein]
other names :
[proteinase 3; Myeloblastin; myeloblastin; proteinase 3; AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigen]
other gene names :
[PRTN3; PRTN3; MBN; MBT; NP4; P29; PR3; ACPA; AGP7; NP-4; PR-3; CANCA; C-ANCA; MBN; PR-3; PR3; NP-4]
host :
Human
sequence length :
254
purity :
>=98% by SDS-PAGE
form :
Liquid in 50mM Sodium Acetate, and 0.1M NaCl, pH 4.5 with 0.02% lubrol.
concentration :
0.47mg/ml
storage stability :
Upon receipt store at -20 degree C in working aliquots. Avoid freeze/thaw cycles. Shipping: Dry Ice.
app notes :
User optimized
other info1 :
Host Note: Human neutrophils. Grade: Highly pure. Protein Type: Native. Biohazard: Non-reactive for HBsAg, Anti-HCV, and Anti-HIV I/II by FDA approved methods. Also negative for viral DNA/RNA for HBV, HIV I, and HCV by PCR.
other info2 :
Dry Ice Shipment: Extra charge may be applied to your shipping cost as dry ice is required to ship this product. Biological Significance: Proteinase 3 also known as PRTN3 is an enzyme which in humans is encoded by the PRTN3 gene. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides.
products categories :
Immunology
ncbi gi num :
1335280
ncbi acc num :
CAA39203.1
uniprot acc num :
P24158
ncbi pathways :
C-MYB Transcription Factor Network Pathway (138073); Common Pathway (106060); Formation Of Fibrin Clot (Clotting Cascade) Pathway (106057); Hemostasis Pathway (106028)
uniprot summary :
PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily. Protein type: Cell cycle regulation; EC 3.4.21.76; Protease. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: cytosol; extracellular matrix; extracellular space; plasma membrane. Molecular Function: enzyme binding; serine-type endopeptidase activity; serine-type peptidase activity. Biological Process: blood coagulation; negative regulation of phagocytosis; positive regulation of cell proliferation
size1 :
0.1 mg
price1 :
575 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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