product summary
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company name :
MyBioSource
product type :
protein
product name :
Purified Native Bordetella pertussis toxin protein
catalog :
MBS5308269
quantity :
0.1 mg
price :
590 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS5308269
products type :
Native Protein
products full name :
Purified Native Bordetella pertussis toxin protein
products short name :
[Bordetella pertussis toxin]
products name syn :
[Bordetella pertussis toxin antigen, Bordetella pertussis protein, B pertussis toxin protein, Pertussis toxin protein, PT protein]
host :
B.pertussis strain NC10739/ACTC 9797
purity :
> 98% by SDS-PAGE.
form :
Liquid in 50mM Sodium Phosphate and 500 mM Sodium Chloride, pH 7.2
concentration :
0.25 mg/ml
storage stability :
Store at 4°C for short term, -20°C to -80°C for long term. Avoid repeat freeze/thaws.
other info1 :
Species: Viral. Protein Type: Native. Biohazard: Use standard laboratory precautions when handling this material.
other info2 :
Biological significance: Pertussis toxin (PT) is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. PT is involved in the colonization of the respiratory tract and the establishment of infection. Research suggests PT may have a therapeutic role in treating a number of common human ailments, including hypertension, viral inhibition, and autoimmune inhibition. Implications in Disease: Pertussis (or whooping cough) is an infection of the respiratory system characterized by a “whooping” sound when the person breathes in. B. pertussis has the ability to inhibit the function of the host's immune system. The toxin, known as pertussis toxin (or PTx), inhibits G protein coupling that regulates an adenylate cyclase-mediated conversion of ATP to cyclic AMP. The end result is phagocytes convert too much ATP to cyclic AMP, which can cause disturbances in cellular signaling mechanisms, and prevent phagocytes from correctly responding to an infection. The infection occurs mostly in children under the age of one when they are unimmunized, or children with faded immunity, normally around the ages 11 through 18. The signs and symptoms are similar to a common cold: runny nose, sneezing, mild cough, and low-grade fever. The patient becomes most contagious during the catarrhal stage of infection, normally two weeks after the coughing begins.
products categories :
Infectious Disease
size1 :
0.1 mg
price1 :
590 USD
size2 :
1 mg
price2 :
2175
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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