product summary
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company name :
MyBioSource
product type :
antibody
product name :
Renin antibody
catalog :
MBS530796
quantity :
0.2 ml
price :
515 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
118
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530796
products type :
Antibody
products full name :
Renin antibody
products short name :
Renin
products name syn :
Monoclonal Renin; Anti-Renin
other names :
renin; Renin; renin; renin; Angiotensinogenase
other gene names :
REN; REN; HNFJ2
uniprot entry name :
RENI_HUMAN
clonality :
Monoclonal
clone :
118
host :
Mouse
reactivity :
No cross reaction with Human
sequence length :
406
specificity :
Mouse and Rat Renin
form :
Supplied as a lyophilized powder
storage stability :
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -80 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
other info1 :
Biological Significance: Renin, also known as an angiotensinogenase is an enzyme that participates in the body's renin-angiotensin system (RAS) that mediates extracellular volume (i.e., that of the blood plasma, lymph and interstitial fluid), and arterial vasoconstriction. Thus, it regulates the body's mean arterial blood pressure.
other info2 :
Immunogen: Renin antibody was raised in mouse using submandibular gland renin as the immunogen.
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Mouse monoclonal Renin antibody
ncbi gi num :
190994
ncbi acc num :
AAA60363.1
uniprot acc num :
P00797
ncbi mol weight :
44,726 Da
ncbi pathways :
ACE Inhibitor Pathway 198763!!Metabolism Of Angiotensinogen To Angiotensins Pathway 685555!!Metabolism Of Proteins Pathway 106230!!Peptide Hormone Metabolism Pathway 771603!!Renin-angiotensin System Pathway 83075!!Renin-angiotensin System Pathway 486
ncbi summary :
Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008]
size :
0.2 ml
price :
515 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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