product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
ADRP antibody
catalog :
MBS530762
quantity :
5 ml
price :
535 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AP125
reactivity :
human, rat, dog
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530762
products type :
Antibody
products full name :
ADRP antibody
products short name :
ADRP
products name syn :
Monoclonal ADRP; Anti-ADRP; Adipophilin
other names :
adipophilin, partial; Perilipin-2; perilipin-2; perilipin 2; Adipophilin; Adipose differentiation-related protein; ADRP
products gene name :
ADRP
other gene names :
PLIN2; PLIN2; ADFP; ADRP; ADFP; ADRP
uniprot entry name :
PLIN2_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
AP125
host :
Mouse
reactivity :
Dog, Human, Rat
sequence length :
437
specificity :
Human ADRP
purity :
Culture supernatant
form :
Tissue culture supernatant with 0.09% NaN3
storage stability :
Store at 4 degree C.
tested application :
Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB)
other info1 :
Biological Significance: Adipophilin / ADRP is a ubiquitous component of lipid droplets. It has been found in milk fat globule membranes and on the surface of lipid droplets in various cultured cell lines inducible by etomoxir. Enhanced expression of Adipophilin / ADRP is a useful marker for pathologies characterized by increased lipid droplet accumulation. Such diseases include atheroma, steatosis, obesity and certain cases of liposarcoma.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: ADRP antibody was raised in mouse using a synthetic peptide corresponding to residues 5-27 from the N-terminus of human adipophilin as the immunogen.
products categories :
Nutrition & Metabolism
products description :
Mouse monoclonal ADRP antibody
ncbi gi num :
1806040
ncbi acc num :
CAA65989.1
uniprot acc num :
Q99541
ncbi mol weight :
48,075 Da
ncbi pathways :
Adipogenesis Pathway 198832!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!HIF-1-alpha Transcription Factor Network Pathway 138045!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!PPARA Activates Gene Expression Pathway 530749!!Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway 119544
ncbi summary :
The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
size :
5 ml
price :
535 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!