product summary
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company name :
MyBioSource
product type :
antibody
product name :
Prohibitin antibody (biotin)
catalog :
MBS530665
quantity :
0.1 mg
price :
715 USD
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
II-14-10
reactivity :
human, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530665
products type :
Antibody
products full name :
Prohibitin antibody (biotin)
products short name :
Prohibitin
products name syn :
Monoclonal Prohibitin; Anti-Prohibitin; Mitochondrial Marker; Prohibitin; Anti Prohibitin
other names :
prohibitin isoform 1; Prohibitin; prohibitin; prohibitin
other gene names :
PHB; PHB; PHB1; HEL-215; HEL-S-54e
uniprot entry name :
PHB_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
II-14-10
host :
Mouse
reactivity :
Chicken, Human, Mouse Pig
sequence length :
272
specificity :
Rat
purity :
Prohibitin antibody (biotin) was purified by Protein G chromatography.
form :
Antibody purified from ascites fluid by protein G chromotography and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
concentration :
0.2 mg/ml
storage stability :
Store at 4 degree C.
tested application :
Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP), Western Blot (WB)
app notes :
IHC-F/p: 2-4 ug/ml. IP: 2 ug/ml protein lysate. WB: 0.5-1 ug/ml
other info1 :
Biological Significance: Prohibitin is an evolutionarily conserved protein located in the inner membrane of mitochondria. PROHIBITIN APPEARS TO BE A VERY RELIABLE MARKER OF MITOCHONDRIA. Prohibitin shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Tag/Conjugate: Biotin. Immunogen: Prohibitin antibody (biotin) was raised in mouse using purified recombinant rat prohibitin protein as the immunogen.
products categories :
Cell Cycle & Cell Death; Conjugated Monoclonal Antibodies
products description :
Mouse monoclonal Prohibitin antibody (biotin)
ncbi gi num :
4505773
ncbi acc num :
NP_002625.1
ncbi gb acc num :
NM_002634.2
uniprot acc num :
P35232
ncbi mol weight :
17,018 Da
ncbi pathways :
Integrated Breast Cancer Pathway 219801
ncbi summary :
This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
size :
0.1 mg
price :
715 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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