product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal LGR4 antibody
catalog :
MBS5306632
quantity :
0.1 mL
price :
760 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[2D1]
reactivity :
human
application :
western blot, flow cytometry, FACS
more info or order :
image
image 1 :
Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant LGR4 protein (Right) or empty vector (Left) detected with LGR4 antibody.
image 2 :
Flow Cytometric analysis of HEK293T cells transfected with either recombinant LGR4 protein (red) or empty vector (blue) stained using LGR4 antibody
product information
catalog number :
MBS5306632
products type :
Antibody
products full name :
Mouse monoclonal LGR4 antibody
products short name :
[LGR4]
products name syn :
[Monoclonal LGR4 antibody, Anti-LGR4 antibody, Leucine rich repeat containing G protein coupled receptor 4 antibody, GPR48 antibody, G protein-coupled receptor 48 antibody, G-protein coupled receptor 48 antibody, LGR4, LGR 4, LGR-4, LGR 4 antibody, LGR-4 antibody]
other names :
[leucine-rich repeat-containing G-protein coupled receptor 4 isoform 1; Leucine-rich repeat-containing G-protein coupled receptor 4; leucine-rich repeat-containing G-protein coupled receptor 4; leucine rich repeat containing G protein-coupled receptor 4; G-protein coupled receptor 48]
products gene name :
[LGR4]
other gene names :
[LGR4; LGR4; GPR48; BNMD17; GPR48]
clonality :
Monoclonal
isotype :
IgG1
clone :
[2D1]
host :
Mouse
reactivity :
Human
purity :
Purified by affinity chromatography.
form :
Liquid in PBS buffer, pH 7.3, with 1% BSA, 50% glycerol and 0.02% sodium azide.
concentration :
0.73mg/ml
storage stability :
4°C short term, -20°C long term. Avoid repeated freeze/thaw cycles.
tested application :
Flow Cytometry (FC/FACS), Western Blot (WB)
app notes :
Usage Recommendations: FC: 1:100, WB: 1:500
image1 heading :
Western Blot (WB)
image2 heading :
Flow Cytometry (FC/FACS)
other info1 :
Immunogen: Human recombinant protein fragment corresponding to amino acids 230-540 of human LGR4 produced in HEK293T cells.
products categories :
Cell Biology
products description :
G protein-coupled receptors (GPCRs) play key roles in a variety of physiologic functions. Members of the leucine-richGPCR (LGR) family, such as GPR48, have multiple N-terminal leucine-rich repeats (LRRs) and a 7-transmembrane domain.
ncbi gi num :
157694513
ncbi acc num :
NP_060960.2
ncbi gb acc num :
NM_018490.3
uniprot acc num :
Q9BXB1
ncbi summary :
The protein encoded by this gene is a G-protein coupled receptor that binds R-spondins and activates the Wnt signaling pathway. This Wnt signaling pathway activation is necessary for proper development of many organs of the body. [provided by RefSeq, Oct 2016]
uniprot summary :
LGR4: a leucine-rich repeat-containing G-protein-coupled receptor. Receptor for R-spondins, potent stimulators of adult stem cell proliferation. A Wnt receptor component that enhances Wnt signaling by soluble R-spondin proteins. Plays an essential role during homeostasis of the adult mouse intestine. Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR. Chromosomal Location of Human Ortholog: 11p14.1. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: G-protein coupled receptor activity; protein binding; transmembrane receptor activity. Biological Process: bone mineralization; bone remodeling; circadian regulation of gene expression; negative regulation of cytokine secretion; negative regulation of toll-like receptor signaling pathway; osteoblast differentiation; spermatogenesis. Disease: Bone Mineral Density Quantitative Trait Locus 17
size1 :
0.1 mL
price1 :
760 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
browse more products
questions and comments