catalog number :
MBS5305972
products full name :
Mouse monoclonal Diphtheria toxin antibody
products short name :
[Diphtheria toxin]
products name syn :
[Diphtheria toxin antibody]
other names :
[diphtheria toxin; Diphtheria toxin; NAD(+)--diphthamide ADP-ribosyltransferase (EC:2.4.2.36)]
other gene names :
[DT; DT]
reactivity :
Reacts with the epitope exposed on free A-subunit and on whole Diphtheria toxin molecule. Does not react with free B-subunit of Diphtheria toxin.
specificity :
Corynebacterium diphteriae
form :
Purified IgG by protein A chromatography, supplied in PBS buffer, pH 7.4 with 0.09% NaN 3
concentration :
8.1 mg/mL
storage stability :
Store at 4°C.
tested application :
ELISA (EIA), Immunoassays
app notes :
MBS530051 can be used in a sandwich immunoassay as a conjugate antibody in conjuction with MBS5305972 as the coating antibody.
other info1 :
Immunogen: Diphtheria toxoid. Biohazard Information: This product contains sodium azide as preservative. Although the amount sodium azide is very small appropiate care must be taken when handling this product. Biological Significance: Diphtheria toxins is an exotoxin secreted by Corynebacterium diphtheriae, the pathogen bacterium that causes diphtheria in humans by gaining entry into the cell cytoplasm and inhibiting protein synthesis.
products categories :
Infectious Disease
ncbi acc num :
CAA24778.1
uniprot summary :
Diphtheria toxin, produced by a phage infecting Corynebacterium diphtheriae, is a proenzyme that, after activation, catalyzes the covalent attachment of the ADP ribose moiety of NAD to elongation factor 2. Fragment A is responsible for enzymatic ADP-ribosylation of elongation factor 2, while fragment B is responsible for binding of toxin to cell receptors and entry of fragment A.