product summary
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company name :
MyBioSource
product type :
antibody
product name :
Factor VII antibody
catalog :
MBS530593
quantity :
0.5 mg
price :
395 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
219
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530593
products type :
Antibody
products full name :
Factor VII antibody
products short name :
Factor VII
products name syn :
Monoclonal Factor VII; Anti-Factor VII; Complement Factor VII
other names :
factor VII; Coagulation factor VII; coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); Proconvertin; Serum prothrombin conversion accelerator; SPCA
other gene names :
F7; F7; SPCA; SPCA
uniprot entry name :
FA7_HUMAN
clonality :
Monoclonal
clone :
219
host :
Mouse
reactivity :
To be determined by end-user
sequence length :
466
specificity :
Human
form :
Lyophilized from 10mM Na3PO4, 0.15M NaCl, 0.01% NaN3, pH 7.4. Reconstitute with deionized water.
storage stability :
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
tested application :
User optimized
other info1 :
Biological Significance: Factor VII is one of the central proteins in the coagulation cascade. It is an enzyme of the serine protease class. The main role of factor VII is to initiate the process of coagulation in conjunction with tissue factor (TF/factor III).
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Factor VII antibody was raised in mouse using human factor VII as the immunogen.
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Mouse monoclonal Factor VII antibody
ncbi gi num :
180334
ncbi acc num :
AAA51983.1
uniprot acc num :
P08709
ncbi mol weight :
49,320 Da
ncbi pathways :
BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway 477138!!Blood Clotting Cascade Pathway 198840!!Circadian Clock Pathway 187173!!Complement And Coagulation Cascades Pathway 198880!!Complement And Coagulation Cascades Pathway 83073!!Complement And Coagulation Cascades Pathway 484!!Extrinsic Pathway Of Fibrin Clot Formation 106058!!Formation Of Fibrin Clot (Clotting Cascade) Pathway 106057!!Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway 106231!!Gamma-carboxylation Of Protein Precursors Pathway 106233
ncbi summary :
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
size :
0.5 mg
price :
395 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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