This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
IFNAR1 antibody
catalog :
MBS530590
quantity :
0.5 mg
price :
2600 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MMHAR-1
reactivity :
human
application :
western blot, ELISA, flow cytometry, FACS, enzyme immunoassay
product information
catalog number :
MBS530590
products type :
Antibody
products full name :
IFNAR1 antibody
products short name :
IFNAR1
products name syn :
Monoclonal IFNAR1; Anti-IFNAR1; IFNAR-1; IFNAR 1; Interferon alpha/beta Receptor 1; IFNAR1
other names :
Interferon (alpha, beta and omega) receptor 1; Interferon alpha/beta receptor 1; interferon alpha/beta receptor 1; interferon (alpha, beta and omega) receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1
products gene name :
IFNAR1
other gene names :
IFNAR1; IFNAR1; AVP; IFRC; IFNAR; IFNBR; IFN-alpha-REC; IFNAR; IFN-R-1; IFN-alpha/beta receptor 1; CRF2-1
uniprot entry name :
INAR1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
MMHAR-1
host :
Mouse
reactivity :
No cross reactivity with Human IFN gamma R1 or R2, Murine IFN alpha/beta R2, Human IL10 R alpha/beta or Human IL20 R beta.
sequence length :
557
specificity :
Human IFN alpha/beta R1
form :
Lyophilized from PBS with 5% trehalose. Reconstitute in 1 ml sterile PBS.
storage stability :
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
tested application :
ELISA (EIA), Flow Cytometry (FC/FACS), Western Blot (WB)
other info1 :
Biological Significance: Interferons (IFNs) are proteins made and released by lymphocytes in response to the presence of pathogens-such as viruses, bacteria, or parasites-or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.
products categories :
Immunology
products description :
Mouse monoclonal IFNAR1 antibody
ncbi gi num :
18255502
ncbi acc num :
AAH21825.1
uniprot acc num :
P17181
ncbi mol weight :
56,046 Da
ncbi pathways :
Cytokine Signaling In Immune System Pathway (366171); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Downstream Signaling In Naive CD8+ T Cells Pathway (138018); Hepatitis B Pathway (694606); Hepatitis C Pathway (173973); Hepatitis C Pathway (173907); Herpes Simplex Infection Pathway (377873); Herpes Simplex Infection Pathway (377865); Immune System Pathway (106386)
ncbi summary :
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. [provided by RefSeq, Jul 2008]
uniprot summary :
IFNAR1: receptor for interferons alpha and beta. Belongs to the type II cytokine family of receptors. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. Tyk2 tyrosine kinase is essential for stable cell surface expression of IFNAR1. Present in all tissues and even on the surface of most IFN-resistant cells. Protein type: Membrane protein, integral; Receptor, cytokine. Chromosomal Location of Human Ortholog: 21q22.11. Cellular Component: integral to plasma membrane; integral to membrane; plasma membrane. Molecular Function: protein binding; interferon receptor activity; interferon-alpha/beta receptor activity. Biological Process: positive regulation of interferon-gamma production; cell surface receptor linked signal transduction; T cell activation; cytokine and chemokine mediated signaling pathway; response to virus; positive regulation of interleukin-1 beta secretion; interferon type I biosynthetic process; JAK-STAT cascade; defense response to virus
size1 :
0.5 mg
price1 :
2600 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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