product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD163 antibody
catalog :
MBS530587
quantity :
0.25 mg
price :
755 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
ED2
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, FACS, immunohistochemistry - paraffin section
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530587
products type :
Antibody
products full name :
CD163 antibody
products short name :
CD163
products name syn :
Monoclonal CD163; Anti-CD163; CD-163; CD 163; CD163
other names :
CD163; Scavenger receptor cysteine-rich type 1 protein M130; scavenger receptor cysteine-rich type 1 protein M130; CD163 molecule; Hemoglobin scavenger receptor; CD_antigen: CD163
products gene name :
CD163
other gene names :
CD163; CD163; M130; MM130; M130; sCD163
uniprot entry name :
C163A_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
ED2
host :
Mouse
reactivity :
To be determined by end-user
sequence length :
1116
specificity :
Rat
form :
Lyophilized from PBS, pH7.2, with 0.01% thimerosal.
storage stability :
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles.
tested application :
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP), Western Blot (WB)
app notes :
IHC-F: 2 ug/ml. IHC-P: 20 ug/ml
other info1 :
Biological Significance: CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages. It is thought this function serves to protect tissues from free hemoglobin-mediated oxidative damage. CD 163 may also play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme.
other info2 :
Immunogen: CD163 antibody was raised in mouse using rat spleen cells as the immunogen.
products categories :
Immunology
products description :
Mouse monoclonal CD163 antibody
ncbi gi num :
5107945
ncbi acc num :
CAB45233.1
uniprot acc num :
Q86VB7
ncbi mol weight :
124,958 Da
ncbi pathways :
Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Scavenging Of Heme From Plasma Pathway 771600!!Vesicle-mediated Transport Pathway 1183600
ncbi summary :
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
size :
0.25 mg
price :
755 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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