This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
CD70 antibody
catalog :
MBS530582
quantity :
1 mL
price :
535 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CLB-2F2
reactivity :
human
application :
immunocytochemistry, flow cytometry, FACS
product information
catalog number :
MBS530582
products type :
Antibody
products full name :
CD70 antibody
products short name :
CD70
products name syn :
Monoclonal CD70; Anti-CD70; CD 70; Bu69; CD70; CD-70
other names :
CD70 antigen; CD70 antigen; CD70 antigen; CD70 molecule; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD_antigen: CD70
products gene name :
CD70
other gene names :
CD70; CD70; CD27L; CD27LG; TNFSF7; CD27L; CD27LG; TNFSF7; CD27-L
uniprot entry name :
CD70_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
CLB-2F2
host :
Mouse
reactivity :
Human CD70
sequence length :
193
form :
Liquid in 20mM TRIS, pH 8.0, with 150mM NaCl, and 10 mg BSA.
concentration :
0.2 mg/ml
storage stability :
Store at 4 degree C. Keep away from light.
tested application :
Flow Cytometry (FC/FACS), Immunofluorescence (IF)
other info1 :
Biological Significance: CD70 (Cluster of Differentiation 70) is a ligand for CD27.
other info2 :
Immunogen: CD70 antibody was raised in mouse using Irradiated Ramos cells as the immunogen.
products categories :
Immunology
products description :
Mouse monoclonal CD70 antibody
ncbi gi num :
4507605
ncbi acc num :
NP_001243.1
ncbi gb acc num :
NM_001252.3
uniprot acc num :
P32970
ncbi mol weight :
60 kDa (predicted detection band MW)
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460)
ncbi summary :
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]
uniprot summary :
CD70: Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. Belongs to the tumor necrosis factor family. Protein type: Membrane protein, integral; Cytokine. Chromosomal Location of Human Ortholog: 19p13. Cellular Component: extracellular space; integral to plasma membrane; plasma membrane. Molecular Function: protein binding; protease binding; cytokine activity; tumor necrosis factor receptor binding; receptor binding. Biological Process: cell proliferation; cell-cell signaling; immune response; signal transduction
size1 :
1 mL
price1 :
535 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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