catalog number :
MBS530570
products full name :
CRP antibody
products short name :
CRP
products name syn :
Monoclonal CRP; Anti-CRP; C-Reactive Protein
other names :
C-reactive protein; C-reactive protein; C-reactive protein; C-reactive protein, pentraxin-related
other gene names :
CRP; CRP; PTX1; PTX1
uniprot entry name :
CRP_HUMAN
specificity :
Specific for C-RP only. No cross reaction with other serum proteins
purity :
Protein A chromatography
form :
Protein A purified and supplied in PBS buffer, pH 7.5 with 0.1% NaN3.
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA), Immunoassays
app notes :
MBS530570 can be used as the capture antibody in a matched pair immunoassay in conjunction with MBS530250 as the detection antibody
other info1 :
Biological Significance: C-reactive protein (CRP) is a protein found in the blood, the levels of which rise in response to inflammation (i.e. C-reactive protein is an acute-phase protein). Its physiological role is to bind to phosphocholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via the C1Q complex.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: CRP antibody was raised in mouse using highly pure immuno grade C-RP as the immunogen.
products categories :
Cardiac Markers
products description :
Mouse monoclonal CRP antibody
products references :
Superparamagnetic bead interactions with functionalized surfaces characterized by an immunomicroarray; Peter Durand Skottrup, Mikkel Fougt Hansen, Jacob Moresco Lange, Maria Deryabina, Winnie Edith Svendsen, Mogens Havsteen Jakobsen, Martin Dufva (Acta Biomaterialia: Volume: 6 Issue: 10 Page: 3936-3946 DOI: 10.1016/j.actbio.2010.04.019)
ncbi acc num :
CAA39671.1
ncbi mol weight :
10,415 Da
ncbi pathways :
Classical Antibody-mediated Complement Activation Pathway 106409!!Complement Cascade Pathway 106405!!Creation Of C4 And C2 Activators Pathway 106407!!IL6-mediated Signaling Events Pathway 137932!!Immune System Pathway 106386!!Initial Triggering Of Complement Pathway 106406!!Innate Immune System Pathway 106387!!Selenium Pathway 198825
ncbi summary :
The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]