product summary
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company name :
MyBioSource
product type :
antibody
product name :
CD163 antibody (biotin)
catalog :
MBS530501
quantity :
0.25 mg
price :
865 USD
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
RM3/1
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530501
products type :
Antibody
products full name :
CD163 antibody (biotin)
products short name :
CD163
products name syn :
Monoclonal CD163; Anti-CD163; CD 163; CD-163; CD163
other names :
CD163; Scavenger receptor cysteine-rich type 1 protein M130; scavenger receptor cysteine-rich type 1 protein M130; CD163 molecule; Hemoglobin scavenger receptor; CD_antigen: CD163
products gene name :
CD163
other gene names :
CD163; CD163; M130; MM130; M130; sCD163
uniprot entry name :
C163A_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
RM3/1
host :
Mouse
reactivity :
Non-Human Primates
sequence length :
1116
specificity :
Human
form :
Lyophilized from PBS, pH 7.2, with 10mg/ml BSA, and 0.01% thimerosal.
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Formalin, Western Blot (WB)
app notes :
IHC-F: 2 ug/ml
other info1 :
Biological Significance: CD163 is a scavenger receptor for the haemoglobin-haptoglobin complex, and is upregulated by glucocorticoids and IL-10. The extracellular portion of the receptor is regularly shed and can be found in the circulation. An important function of CD163 seems to be in the adhesion of monocytes to activated endothelial cells.
other info2 :
Tag/Conjugate: Biotin. Immunogen: CD163 antibody (biotin) was raised in mouse using human monocytes as the immunogen.
products categories :
Immunology; Conjugated Monoclonal Antibodies
products description :
Mouse monoclonal CD163 antibody (biotin)
ncbi gi num :
5107945
ncbi acc num :
CAB45233.1
uniprot acc num :
Q86VB7
ncbi mol weight :
124,958 Da
ncbi pathways :
Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Scavenging Of Heme From Plasma Pathway 771600!!Vesicle-mediated Transport Pathway 1183600
ncbi summary :
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
size :
0.25 mg
price :
865 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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