This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
CD16 antibody
catalog :
MBS530474
quantity :
0.1 mg
price :
330 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3G8
reactivity :
human
application :
flow cytometry, FACS
product information
catalog number :
MBS530474
products type :
Antibody
products full name :
CD16 antibody
products short name :
CD16
products name syn :
Monoclonal CD16; Anti-CD16; CD-16; CD 16; FcgRIII; CD16 FcgRIII; CD16
other names :
CD16, partial; Low affinity immunoglobulin gamma Fc region receptor III-A; low affinity immunoglobulin gamma Fc region receptor III-A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); CD16a antigen; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; CD_antigen: CD16a
products gene name :
CD16
other gene names :
FCGR3A; FCGR3A; CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA; CD16A; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa
uniprot entry name :
FCG3A_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
3G8
host :
Mouse
reactivity :
To be determined by end-user
sequence length :
233
specificity :
Human
purity :
> 95% pure. CD16 antibody was purified by Protein A chromatography.
form :
50mM Na3PO4, pH 7.5, with 100mM KCL, 150mM NaCl, and 0.5 mg/ml gentamycin sulfate.
concentration :
1.0 mg/ml
storage stability :
Store at 4 degree C.
tested application :
Flow Cytometry (FC/FACS)
app notes :
FC: 5 ug/ml
other info1 :
Biological Significance: Human CD16 is a low affinity receptor for complexed IgG and occurs in two distinct forms, as a glycosyl phosphtidyl inositol (GPI) anchored protein in granulocytes, and as an integral membrane protein on NK cells and macrophages.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: CD16 antibody was raised in mouse using human polymorphonuclear leukocytes as the immunogen.
products categories :
Immunology
products description :
Mouse monoclonal CD16 antibody
ncbi gi num :
8176551
ncbi acc num :
AAB33925.2
uniprot acc num :
P08637
ncbi mol weight :
29,089 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!FCGR Activation Pathway 771578!!Fc Gamma R-mediated Phagocytosis Pathway 114228!!Fc Gamma R-mediated Phagocytosis Pathway 106590!!Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway 771577!!Immune System Pathway 106386!!Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway 106413!!Innate Immune System Pathway 106387!!Leishmaniasis Pathway 144181!!Leishmaniasis Pathway 144028
ncbi summary :
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
330 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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