catalog number :
MBS530450
products full name :
Somatostatin antibody
products short name :
Somatostatin
products name syn :
Monoclonal Somatostatin; Anti-Somatostatin; SS; SST; SOM; Growth hormone inhibitory hormone; GHIH; Somatotropin release inhibiting factor; SRIF; Somatotropin release inhibiting hormone; SRIH
other names :
Somatostatin; Somatostatin; somatostatin; somatostatin; Growth hormone release-inhibiting factor
other gene names :
SST; SST; SMST
uniprot entry name :
SMS_HUMAN
form :
Lyophilised from 1 ml tissue culture supernatant with thimerosol. Reconsitute with 1 ml distilled water.
storage stability :
Store at 4 degree C. Once reconstituted store in aliquots at - 20 degree C.
tested application :
Immunohistochemistry (IHC)
app notes :
IHC: 1:50-1:200
other info1 :
Biological Significance: Product Uses: Monoclonal Somatostatin antibody specific for Human Somatostatin for use in Immunohistochemistry.
other info2 :
Immunogen: Somatostatin antibody was raised in rat using somatostatin conjugated to thyroglobulin as the immunogen.
products categories :
Hormones & Steroids
products description :
Rat monoclonal Somatostatin antibody
ncbi acc num :
AAH32625.1
ncbi mol weight :
12,736 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastric Acid Secretion Pathway (154409); Gastric Acid Secretion Pathway (154383); Peptide Ligand-binding Receptors Pathway (106358); SIDS Susceptibility Pathways (198901); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
ncbi summary :
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]
uniprot summary :
SST: Somatostatin inhibits the release of somatotropin. Belongs to the somatostatin family. Protein type: Secreted, signal peptide; Secreted; Hormone. Chromosomal Location of Human Ortholog: 3q28. Cellular Component: extracellular space; cell soma; extracellular region. Molecular Function: hormone activity. Biological Process: response to drug; synaptic transmission; G-protein coupled receptor protein signaling pathway; negative regulation of cell proliferation; hyperosmotic response; cell surface receptor linked signal transduction; cell-cell signaling; induction of apoptosis by hormones; response to heat; response to steroid hormone stimulus; digestion; response to amino acid stimulus; regulation of cell migration; response to nutrient