This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Androgen Receptor antibody
catalog :
MBS530369
quantity :
0.1 mg
price :
545 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AR 441
reactivity :
human, dog
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
product information
catalog number :
MBS530369
products type :
Antibody
products full name :
Androgen Receptor antibody
products short name :
Androgen Receptor
products name syn :
Monoclonal Androgen Receptor; Anti-Androgen Receptor; AR
other names :
androgen receptor; Androgen receptor; androgen receptor; androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4
other gene names :
AR; AR; KD; AIS; AR8; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; DHTR; NR3C4
uniprot entry name :
ANDR_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
AR 441
host :
Mouse
reactivity :
Dog
sequence length :
917
specificity :
Human
purity :
Androgen Receptor antibody was purified by Protein G chromatography.
form :
Antibody purified from ascites fluid by protein G chromotography and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
concentration :
0.2 mg/ml
storage stability :
Store at 4 degree C.
tested application :
Gel Shift, Immunofluorescence (IF),Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP), Western Blot (WB)
app notes :
Gel Shift: 1 mg/ml. IHC-F: 1:25. IHC-P: 1:25. IP: 2 ug/mg protein lysate
other info1 :
Biological Significance: The androgen receptor (AR), is a type of nuclear receptor that is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The main function of the androgen receptor is as a DNA-binding transcription factor that regulates gene expression.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: Androgen receptor antibody was raised in mouse using a synthetic peptide from human AR as the immunogen.
products categories :
Hormones & Steroids
products description :
Mouse monoclonal Androgen Receptor antibody
ncbi gi num :
178882
ncbi acc num :
AAA51772.1
uniprot acc num :
P10275
ncbi mol weight :
44,643 Da
ncbi pathways :
Activated PKN1 Stimulates Transcription Of AR (androgen Receptor) Regulated Genes KLK2 And KLK3 Pathway 1183588!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Androgen Receptor Signaling Pathway 198806!!Coregulation Of Androgen Receptor Activity Pathway 138085!!FOXA1 Transcription Factor Network Pathway 137979!!Gene Expression Pathway 105937!!Generic Transcription Pathway 105938!!IL-6 Signaling Pathway 198864!!Integrated Breast Cancer Pathway 219801!!Integrated Pancreatic Cancer Pathway 711360
ncbi summary :
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
545 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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