catalog number :
MBS5303681
products type :
Native Protein
products full name :
CFP10 protein
products short name :
[CFP10]
products name syn :
[ESAT-6-like protein; esxB protein; Secreted antigenic protein MTSA10; 10 kDa culture filtrate antigen; CFP-10; CFP 10]
other names :
[CFP10, partial]
products gene name :
[CFP10]
purity :
> 95% by SDS-PAGE
form :
Liquid in 10mM PBS, pH 7.4, with 50% Glycerol.
concentration :
5.2 mg/ml
storage stability :
Shipping: Blue ice. Upon receipt aliquot and store at -20°C or below. Avoid repeated freeze/thaw cycles.
tested application :
ELISA (EIA)
app notes :
Supplied with a hist-tag.
other info1 :
Grade: Recombinant. Protein Type: Native. Biological Significance: CFP10 is an antigen that contributes to the virulence Mycobacterium tuberculosis. CFP-10 forms a tight 1:1 heterodimeric complex with 6kDaA early secreted antigen target (ESAT-6). In the mycobacterial cell, these two proteins are interdependent on each other for stability. The ESAT-6/CFP-10 complex is secreted by the ESX-1 secretion system, also known as the RD1 region. The RD1 region is genomic and is present in all strains of Mycobacterium tuberculosis. Mycobacterium tuberculosis uses this ESX-1 secretion system to deliver virulence factors into host macrophage and monocyte white blood cells during infection. Biohazard: Use standard laboratory precautions when handling this material.
other info2 :
Species: Mycobacterium tuberculosis
products categories :
Infectious Disease; Native Protein
products description :
Purified native CFP10 protein for use in IVD diagnostics
ncbi acc num :
AHN50412.1