catalog number :
MBS530360
products full name :
Hexokinase Type 1 antibody
products short name :
Hexokinase Type 1
products name syn :
Monoclonal Hexokinase Type 1; Anti-Hexokinase Type 1; Hexokinase Type -1; Hexokinase Type 1
other names :
hexokinase type 1, partial; Hexokinase-1; hexokinase-1; hexokinase 1; Brain form hexokinase; Hexokinase type I; HK I
other gene names :
HK1; HK1; HKD; HKI; HXK1; HMSNR; HK1-ta; HK1-tb; HK1-tc; HK I
uniprot entry name :
HXK1_HUMAN
reactivity :
Bovine, Mouse
form :
Ascites fluid containing NaN3.
storage stability :
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
tested application :
Western Blot (WB)
app notes :
WB: 1:100-1:500
other info1 :
Biological Significance: A hexokinase is an enzyme that phosphorylates a six-carbon sugar, a hexose, to a hexose phosphate. In most tissues and organisms, glucose is the most important substrate of hexokinases, and glucose-6-phosphate the most important product. Genes that encode hexokinase have been discovered in each domain of life, ranging from bacteria, yeast, and plants to humans and other vertebrates.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: Hexokinase type 1 antibody was raised in mouse using rat type I hexokinase as the immunogen.
products categories :
Proteases, Inhibitors, & Enzymes
products description :
Mouse monoclonal Hexokinase Type 1 antibody
ncbi acc num :
CAA47379.1
ncbi mol weight :
101,085 Da
ncbi pathways :
Amino Sugar And Nucleotide Sugar Metabolism Pathway 82979!!Amino Sugar And Nucleotide Sugar Metabolism Pathway 350!!Biosynthesis Of Antibiotics Pathway 1144997!!Butirosin And Neomycin Biosynthesis Pathway 145809!!Butirosin And Neomycin Biosynthesis Pathway 145786!!Carbohydrate Digestion And Absorption Pathway 170720!!Carbohydrate Digestion And Absorption Pathway 170654!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Central Carbon Metabolism In Cancer Pathway 1059538
ncbi summary :
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. [provided by RefSeq, Apr 2009]