product summary
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company name :
MyBioSource
product type :
antibody
product name :
AFP antibody
catalog :
MBS530345
quantity :
1 mg
price :
280 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6127435
reactivity :
human
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530345
products type :
Antibody
products full name :
AFP antibody
products short name :
AFP
products name syn :
Monoclonal AFP; Anti-AFP; alpha-Fetoprotein; alpha Fetoprotein
other names :
Alpha-fetoprotein; Alpha-fetoprotein; alpha-fetoprotein; alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin
products gene name :
AFP
other gene names :
AFP; AFP; AFPD; FETA; HPAFP; HPAFP
uniprot entry name :
FETA_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
6127435
host :
Mouse
reactivity :
Human
sequence length :
609
form :
Supplied as a liquid in PBS, pH 7.0, with 0.02% NaN3.
concentration :
Typically 2-5 mg/ml
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
User optimized
app notes :
MBS530345 can be used as the detection antibody in a matched pair immunoassay in conjunction with MBS530323 as the capture antibody
other info1 :
Biological Significance: Alpha-fetoprotein (AFP) is a protein that in humans is encoded by the AFP gene. Alpha-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem on chromosome 4.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: AFP antibody was raised in mouse using AFP from cord blood as the immunogen.
products categories :
Cancer
products description :
Mouse monoclonal AFP antibody
ncbi gi num :
20379787
ncbi acc num :
AAH27881.1
uniprot acc num :
P02771
ncbi mol weight :
68,678 Da
ncbi pathways :
Direct P53 Effectors Pathway (137939); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Glucocorticoid Receptor Regulatory Network Pathway (138014); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388)
ncbi summary :
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008]
uniprot summary :
AFP: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Dimeric and trimeric forms have been found in addition to the monomeric form. Plasma. Synthesized by the fetal liver and yolk sac. Belongs to the ALB/AFP/VDB family. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 4q13.3. Cellular Component: extracellular space; cytoplasm. Molecular Function: metal ion binding. Biological Process: transport; progesterone metabolic process; ovulation from ovarian follicle. Disease: Alpha-fetoprotein Deficiency; Alpha-fetoprotein, Hereditary Persistence Of
size1 :
1 mg
price1 :
280 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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