product summary
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company name :
MyBioSource
product type :
antibody
product name :
Filamin A antibody
catalog :
MBS530311
quantity :
0.1 ml
price :
605 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M95041
reactivity :
human, cow
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS530311
products type :
Antibody
products full name :
Filamin A antibody
products short name :
Filamin A
products name syn :
Monoclonal Filamin A; Anti-Filamin A
other names :
filamin-A isoform 1; Filamin-A; filamin-A; filamin A, alpha; Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial actin-binding protein; Filamin-1; Non-muscle filamin
other gene names :
FLNA; FLNA; FLN; FMD; MNS; OPD; ABPX; CSBS; CVD1; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280; FLN; FLN1; FLN-A; ABP-280
uniprot entry name :
FLNA_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
M95041
host :
Mouse
reactivity :
Bovine
sequence length :
2639
specificity :
Human
form :
Ascites fluid.
storage stability :
Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
tested application :
Immunoprecipitation (IP), Immunofluorescence (IF), Western Blot (WB)
app notes :
WB: 1:250-1:1,000. IF: 1:50-1:200
other info1 :
Biological Significance: Filamin is a structural protein that forms flexible cross-links between two actin filaments. Filamin is a homodimer of polypeptide chains each joined to the other at one end with an actin binding site ath the other. It is present in smooth muscle, fibroblasts, platelets and lymphocytes. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.
other info2 :
Immunogen: Filamin A antibody was raised in mouse using human platelet protein as the immunogen.
products categories :
Cancer
products description :
Mouse monoclonal Filamin A antibody
ncbi gi num :
116063573
ncbi acc num :
NP_001447.2
ncbi gb acc num :
NM_001456.3
uniprot acc num :
P21333
ncbi mol weight :
280,018 Da
ncbi pathways :
Androgen Receptor Signaling Pathway 198806!!Cell Junction Organization Pathway 160966!!Cell-Cell Communication Pathway 477132!!Cell-extracellular Matrix Interactions Pathway 160967!!Focal Adhesion Pathway 198795!!Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!GP1b-IX-V Activation Signalling Pathway 187205!!Hemostasis Pathway 106028!!MAPK Signaling Pathway 198779
ncbi summary :
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
size :
0.1 ml
price :
605 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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