catalog number :
MBS530309
products full name :
Cytokeratin 18 antibody (FITC)
products short name :
Cytokeratin 18
products name syn :
Monoclonal Cytokeratin 18; Anti-Cytokeratin 18; Cytokeratin -18; Cytokeratin 18; Keratin K18
other names :
cytokeratin 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; keratin 18, type I; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
other gene names :
KRT18; KRT18; K18; CYK18; CYK18; CK-18; K18
uniprot entry name :
K1C18_HUMAN
reactivity :
Bovine, Dog, Hamster, Human, Mouse, Pig, Rat, Sheep,
specificity :
Human cytokeratin 18
purity :
Protein A affinity chromatography
form :
Supplied as a liquid, with 0.09% NaN3
storage stability :
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
tested application :
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Formalin/Paraffin
app notes :
IHC-F: 1:10. IHC-P: 1:10
other info1 :
Biological Significance: Cytokeratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Tag/Conjugate: FITC. Immunogen: Cytokeratin 18 antibody (FITC) was raised in mouse using human cytokeratin 18 from HeLa cytoskeletal preparation as the immunogen.
products categories :
Cell Biology ; Conjugated Monoclonal Antibodies
products description :
Mouse monoclonal Cytokeratin 18 antibody (FITC)
ncbi acc num :
CAA31375.1
ncbi mol weight :
48,058 Da
ncbi pathways :
Caspase Cascade In Apoptosis Pathway 137974!!EGFR1 Signaling Pathway 198782!!Pathogenic Escherichia Coli Infection Pathway 83103!!Pathogenic Escherichia Coli Infection Pathway 672459!!Pathogenic Escherichia Coli Infection Pathway 516
ncbi summary :
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]