catalog number :
MBS530284
products full name :
Human Growth Hormone antibody
products short name :
Growth Hormone
products name syn :
Monoclonal Human Growth Hormone; Anti-Human Growth Hormone; hGH; Somatotropin
other names :
growth hormone; Somatotropin; somatotropin; growth hormone 1; Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone
other gene names :
GH1; GH1; GH; GHN; GH-N; hGH-N; IGHD1B; GH; GH-N
uniprot entry name :
SOMA_HUMAN
reactivity :
To be determined by end-user
purity :
Human Growth Hormone antibody was purified by chromatography on protein G Sepharose.
form :
Protein G purified and supplied in PBS, pH 7.4, 0.1 % NaN3.
storage stability :
Store at 4 degree C.
tested application :
ELISA (EIA)
other info1 :
Biological Significance: Growth hormone (GH) is a protein-based peptide hormone. It stimulates growth, cell reproduction and regeneration in humans and other animals. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by the somatotroph cells within the lateral wings of the anterior pituitary gland.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: Human growth hormone antibody was raised in mouse using recombinant human growth hormone as the immunogen.
products categories :
Hormones & Steroids
products description :
Mouse monoclonal Human Growth Hormone antibody
ncbi acc num :
AAA98618.1
ncbi mol weight :
20,201 Da
ncbi pathways :
Adipogenesis Pathway 198832!!Cytokine Signaling In Immune System Pathway 366171!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Endochondral Ossification Pathway 198812!!Growth Hormone Receptor Signaling Pathway 477128!!Immune System Pathway 106386!!Jak-STAT Signaling Pathway 83077!!Jak-STAT Signaling Pathway 488!!Metabolism Of Proteins Pathway 106230
ncbi summary :
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008]