This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
PAP antibody
catalog :
MBS530241
quantity :
1 mg
price :
250 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
M01010922
reactivity :
human
application :
enzyme immunoassay
product information
catalog number :
MBS530241
products type :
Antibody
products full name :
PAP antibody
products short name :
PAP
products name syn :
Monoclonal PAP; Anti-PAP; Prostatic Acid Phosphatase; Anti PAP; PAP
other names :
prostatic acid phosphatase; Prostatic acid phosphatase; prostatic acid phosphatase; acid phosphatase, prostate; 5'-nucleotidase (EC:3.1.3.5); 5'-NT
products gene name :
PAP
other gene names :
ACPP; ACPP; ACP3; 5'-NT; ACP-3; PAP; 5'-NT; TMPase
uniprot entry name :
PPAP_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
M01010922
host :
Mouse
reactivity :
Human PAP
sequence length :
386
form :
PBS, pH 7.5, with 0.1% NaN3.
storage stability :
Store at 4 degree C.
tested application :
ELISA (EIA)
app notes :
Matched pair antibody available for PAP antibody: MBS530305
other info1 :
Biological Significance: Prostatic acid phosphatase (PAP), also prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. It may be found in increased amounts in men who have prostate cancer or other diseases. The highest levels of acid phosphatase are found in metastasized prostate cancer.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Immunogen: PAP antibody was raised in mouse using highly pure human PAP as the immunogen.
products categories :
Cancer
products description :
Mouse monoclonal PAP antibody
ncbi gi num :
189613
ncbi acc num :
AAA60021.1
uniprot acc num :
P15309
ncbi mol weight :
40,443 Da
ncbi pathways :
Riboflavin Metabolism Pathway (83012); Riboflavin Metabolism Pathway (398)
ncbi summary :
This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]
uniprot summary :
ACPP: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Belongs to the histidine acid phosphatase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; EC 3.1.3.2; Phosphatase; Cofactor and Vitamin Metabolism - riboflavin; EC 3.1.3.5. Chromosomal Location of Human Ortholog: 3q22.1. Cellular Component: multivesicular body; extracellular space; Golgi cisterna; lysosomal membrane; apical part of cell; integral to membrane; plasma membrane; intracellular; vesicle membrane; nucleus; filopodium; secretory granule. Molecular Function: 5 -nucleotidase activity; choline binding; identical protein binding; acid phosphatase activity; protein homodimerization activity; phosphoric monoester hydrolase activity; thiamin phosphate phosphatase activity. Biological Process: thiamin metabolic process; dephosphorylation; positive regulation of adenosine receptor signaling pathway; nucleotide metabolic process; regulation of sensory perception of pain; adenosine metabolic process; purine base metabolic process
size1 :
1 mg
price1 :
250 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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