This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
AChE antibody
catalog :
MBS530228
quantity :
0.1 mg
price :
415 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
303630
reactivity :
human
application :
immunohistochemistry, immunoprecipitation, enzyme immunoassay
product information
catalog number :
MBS530228
products type :
Antibody
products full name :
AChE antibody
products short name :
AChE
products name syn :
Monoclonal AChE; Anti-AChE; Acetylcholinesterase
other names :
acetylcholinesterase; Acetylcholinesterase; acetylcholinesterase; acetylcholinesterase (Yt blood group)
products gene name :
AChE
other gene names :
ACHE; ACHE; YT; ACEE; ARACHE; N-ACHE; AChE
uniprot entry name :
ACES_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
303630
host :
Mouse
reactivity :
To be determined by end-user
sequence length :
614
specificity :
Human
form :
PBS, pH 7.6, with 0.1% NaN3.
storage stability :
Store at 4 degree C.
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP)
other info1 :
Biological Significance: Acetylcholinesterase, also known as AChE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. It is mainly found at neuromuscular junctions and cholinergic nervous system, where its activity serves to terminate synaptic transmission.
other info2 :
Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Immunogen: AChE antibody was raised in mouse using AChE from human erythrocytes as the immunogen.
products categories :
Neuroscience
products description :
Mouse monoclonal AChE antibody
ncbi gi num :
177975
ncbi acc num :
AAA68151.1
uniprot acc num :
P22303
ncbi mol weight :
58,352 Da
ncbi pathways :
ATF-2 Transcription Factor Network Pathway 138006!!Acetylcholine Synthesis Pathway 198820!!Biogenic Amine Synthesis Pathway 198793!!Cholinergic Synapse Pathway 217716!!Glycerophospholipid Biosynthesis Pathway 645313!!Glycerophospholipid Metabolism Pathway 82989!!Glycerophospholipid Metabolism Pathway 364!!Integrated Pancreatic Cancer Pathway 711360!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976
ncbi summary :
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
415 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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